Evidence map›Paper›PMID 42374536›Full record

ArticleAntimicrobial resistance and infection control2026

The effect of a proprietary chlorine-stabilizing surface-coating formulation on healthcare environment disinfection in multidrug-resistant bacteria isolation rooms.

Yael Givon-Cohen, Nadav Abel, Tatiana Vander, Olga Libkind, Pasha Gur, Shahar Frechtman-Berger, Keren Anat Resnick, Jacob Moran-Gilad, Oren Zimhony

Abstract read
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In one paragraph

Article in Antimicrobial resistance and infection control, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yael Givon-CohenInfectious Diseases Unit, Faculty of Medicine, Kaplan Medical Center, Hebrew University of Jerusalem, Pasternak St 1 Rehovot, Rehovot, POB1 76100, Israel.
Nadav AbelHerzfeld Geriatric Rehabilitation Hospital, Gedera, Israel.
Tatiana VanderHerzfeld Geriatric Rehabilitation Hospital, Gedera, Israel.
Olga LibkindHerzfeld Geriatric Rehabilitation Hospital, Gedera, Israel.
Pasha GurHerzfeld Geriatric Rehabilitation Hospital, Gedera, Israel.
Shahar Frechtman-BergerDepartment of Health Policy and Management, School of Public Health, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Keren Anat ResnickDepartment of Health Policy and Management, School of Public Health, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Jacob Moran-GiladDepartment of Health Policy and Management, School of Public Health, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Oren ZimhonyInfectious Diseases Unit, Faculty of Medicine, Kaplan Medical Center, Hebrew University of Jerusalem, Pasternak St 1 Rehovot, Rehovot, POB1 76100, Israel. Oren_Z@clalit.org.il.

Funding

Biofence Ltd. The implementation of OxiLast™ in this study was funded by Biofence Ltd. The funder had no role in environmental sampling, microbiologic processing, data analysis, or interpretation, which were performed independently by the study investigators.
6 · The paper itself

Abstract

objectiveOxiLast™ is a surface coating formulation that extends the antimicrobial effect of chlorine-based disinfectants. We sought to test it in a healthcare environment.

designControlled quasi-experimental study with parallel groups and repeated measures, conducted in isolation rooms of chronically ventilated patients, carriers of carbapenem-resistant Acinetobacter baumannii (CRAB).

methodsStandard sodium dichloroisocyanurate (NaDCC) disinfection was supplemented with OxiLast™ daily for 28 days at five patient stations, followed by twice-weekly application for 21 days. In parallel, six control stations were cleaned daily by NaDCC alone throughout the study. Environmental sampling targeted high touch surfaces adjacent to patient beds. Quantitative colony counts (CFU/cm2) and qualitative detection of CRAB and methicillin-resistant Staphylococcus aureus (MRSA) were performed at four time points: Day 0 (baseline), 21, 42, and 49. A decrease in environmental bioburden (target <5 CFU/cm

resultsBaseline contamination averaged 1,272 CFU/cm

conclusionsThese findings provide proof-of-concept for an extended-action protocol using OxiLast™ adjunct to NaDCC. The impact of this intervention on MDRO transmission and clinical infections should be further studied.

Indexed as

ChlorineDisinfectantsDisinfectionDrug Resistance, Multiple, BacterialAcinetobacter baumanniiColony Count, MicrobialCross InfectionHumansMethicillin-Resistant Staphylococcus aureusTriazinesChlorineDisinfectantsTriazinestroclosene

Identifiers

PMID42374536
PMCPMC13613773

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.