ArticleJournal of nanobiotechnology2026
A zinc-coordinated cascade-responsive therapeutic nanoassembly for remodeling the pathological microenvironment and restoring mitochondrial homeostasis in spinal cord injury.
Chunyu Xiang, Xiaodong He, Fengshuo Guo, Haowen Luo, Liumin He, Wanguo Liu, Rui Gu
Abstract read
In one paragraphArticle in Journal of nanobiotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
7 authors.
Chunyu XiangDepartment of Orthopedic Surgery, China-Japan Union Hospital of Jilin University, Changchun, 130033, P. R. China.
Xiaodong HeDepartment of Orthopedic Surgery, China-Japan Union Hospital of Jilin University, Changchun, 130033, P. R. China.
Fengshuo GuoDepartment of Orthopedic Surgery, China-Japan Union Hospital of Jilin University, Changchun, 130033, P. R. China.
Haowen LuoDepartment of Orthopedic Surgery, China-Japan Union Hospital of Jilin University, Changchun, 130033, P. R. China.
Liumin HeDepartment of Spine Surgery, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, P.R. China.
Wanguo LiuDepartment of Orthopedic Surgery, China-Japan Union Hospital of Jilin University, Changchun, 130033, P. R. China. liuwanguo6016@jlu.edu.cn.
Rui GuDepartment of Orthopedic Surgery, China-Japan Union Hospital of Jilin University, Changchun, 130033, P. R. China. gurui@jlu.edu.cn.
Funding
"Chunlei Plan" Project of China Japan Union Hospital of Jilin University 2024CL09International Cooperative Project of Talent Cultivation "Xinghai Project" at the China-Japan Union Hospital of Jilin University HLH202404Jilin Province Science and Technology Development Plan 20260601070RC, YDZJ202402063CXJDMedical + X" Cross Innovation Team "Unveiling the List and Taking Command" Construction Project of Bethune Medical College of Jilin University 2024JBGS06National Natural Science Foundation of China 82271411, 51803072
6 · The paper itselfAbstract
Secondary injury after spinal cord injury (SCI) is sustained by coupled oxidative stress and inflammation, which drives neuronal apoptosis and bioenergetic failure. Here, a cascade-responsive Zn
Indexed as
MitochondriaSpinal Cord InjuriesZincAnimalsAntioxidantsCatechinHomeostasisMiceNeuronsOxidative StressProanthocyanidinsReactive Oxygen SpeciesSuperoxide Dismutase 2AntioxidantsCatechinProanthocyanidinsReactive Oxygen SpeciesSuperoxide Dismutase 2ZincMitochondrial homeostasisPolyarginineProcyanidinSpinal cord injuryZinc-coordinated nanoassembly
Identifiers
PMID42374452
PMCPMC13576143
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