Evidence map›Paper›PMID 42374343›Full record

ArticleBMC surgery2026

Factors influencing postoperative pain catastrophizing in patients with lower limb trauma and development of a nomogram prediction model.

Jia Xie, Yuan Chen, Jingjing Fan, Jing Xu, Zhongbao Zhang

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Article in BMC surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Jia XieDepartment of Orthopedics, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, China.
Yuan ChenDepartment of Orthopedics, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, China.
Jingjing FanDepartment of Orthopedics, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, China.
Jing XuDepartment of Orthopedics, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, China.
Zhongbao ZhangDepartment of Rehabilitation Medicine, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Qinhuai District, Nanjing City, Jiangsu Province, 210006, China. zbbxj2020@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to examine the determinants of postoperative pain catastrophizing among surgical patients with lower limb trauma and to develop a nomogram for individualized risk prediction.

methodsData encompassing demographic characteristics, Injury Severity Score (ISS), preoperative Numerical Rating Scale (NRS) for pain, Hospital Anxiety and Depression Scale (HADS) scores, and Fear-Avoidance Beliefs Questionnaire (FABQ) scores were collected. The level of pain catastrophizing was measured postoperatively using the Pain Catastrophizing Scale (PCS). The total sample of 320 patients was randomly allocated into a training set (n = 224) and a validation set (n = 96) at a 7:3 ratio. Independent factors identified through logistic regression analysis were utilized to construct a nomogram. The model's predictive performance was assessed via receiver operating characteristic (ROC) analysis, calibration curves, and decision curve analysis (DCA).

resultsEducational attainment at college level or above served as a protective factor. In contrast, higher scores on the NRS, ISS, HADS, and FABQ were significant risk factors. The nomogram exhibited robust discriminative ability, with area under the curve (AUC) values of 0.850 (95% CI: 0.797-0.904) in the training set and 0.815 (95% CI: 0.718-0.911) in the validation set. Calibration analysis indicated good fit, and DCA confirmed favorable clinical net benefit across a range of threshold probabilities.

conclusionThe incidence of postoperative pain catastrophizing is considerable among patients with lower limb trauma and is influenced by multiple factors including trauma severity, educational level, anxiety/depression, fear-avoidance beliefs, and pain intensity. The constructed nomogram prediction model, based on independent influencing factors, exhibits good discrimination, calibration, and clinical utility, effectively predicting the risk of postoperative pain catastrophizing.

Indexed as

CatastrophizationLeg InjuriesLower ExtremityNomogramsPostoperative PainAdultFemaleHumansMaleMiddle AgedPain MeasurementRisk FactorsInfluencing factorsLower limb traumaNomogram prediction modelPain catastrophizing

Identifiers

PMID42374343
PMCPMC13576296

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.