Evidence map›Paper›PMID 42374251›Full record

ArticleBMC gastroenterology2026

Association of postoperative day 1 procalcitonin levels with short-term mortality after liver transplantation: a single-center retrospective cohort study.

Tong Chen, Hantao Mai, Haoran Li, Xiaoxin Zhong, Ning Wang, Peng Hao, Ruilian Guo, Hongwei Han, Kelin Zhang, Guifang Zhong and 6 more

Abstract read
In one paragraph

Article in BMC gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Tong Chen *Department of Surgical Intensive Care Unit, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Hantao Mai *Department of Liver Transplantation Intensive Care Unit, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Haoran LiDepartment of Surgical Intensive Care Unit, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Xiaoxin ZhongDepartment of Breast Surgery, The Third People's Hospital of Huizhou, Huizhou, Guangdong, China.
Ning WangDepartment of Surgical Intensive Care Unit, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Peng HaoDepartment of Surgical Intensive Care Unit, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Ruilian GuoDepartment of Liver Transplantation Intensive Care Unit, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Hongwei HanDepartment of Liver Transplantation Intensive Care Unit, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Kelin ZhangDepartment of Surgical Intensive Care Unit, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Guifang ZhongDepartment of Surgical Intensive Care Unit, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Huihua ChengDepartment of Surgical Intensive Care Unit, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Benhua JiangDepartment of Surgical Intensive Care Unit, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Sicong ZhuDepartment of Surgical Intensive Care Unit, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Suyuan ZhuangDepartment of Surgical Intensive Care Unit, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Yantao ChenDepartment of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China. chenyant@mail.sysu.edu.cn.
Qing HeDepartment of Surgical Intensive Care Unit, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China. heqing@mail.sysu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative complications, especially infections, are important causes of poor prognosis after liver transplantation. Procalcitonin (PCT) has been proven to be a sensitive marker of infection and inflammation in many diseases. As a result, the purpose of this study was to determine the connection between early postoperative PCT levels and mortality in liver transplant patients.

methodsWe included 205 liver transplant recipients who underwent orthotopic allogeneic liver transplantation at Sun Yat-sen University's Sun Yat-sen Memorial Hospital. We grouped the patients according to the tertile of PCT levels on postoperative day one (POD 1) and divided the patients into three groups: Q1 (≤ 2.0 ng/ml), Q2 (2.1-5.0 ng/ml), and Q3 (≥ 5.1 ng/ml). To analyze the curvilinear association between PCT levels and 90-day mortality and in-hospital mortality, we used Spearman's rank correlation coefficient. The Kaplan-Meier method was used to assess survival rates at 30, 60 and 90 days after liver transplantation. The Log-rank test was used to analyze differences in survival rates between different PCT groups.

resultsHigher POD1 PCT levels were associated with increased 90-day and in-hospital mortality. Furthermore, this study revealed a statistically significant decrease in ICU-free days at 28-day, hospital-free days at 28-day, CRRT-free hours at 28-day, and hospital-free days at 60-day among patients in the group of high PCT level.

conclusionsHigher POD1 PCT levels were associated with worse short-term postoperative outcomes after liver transplantation. However, POD1 PCT should be interpreted as a potential early risk-associated biomarker rather than as an established independent prognostic factor.

Indexed as

Liver TransplantationPostoperative ComplicationsProcalcitoninAdultBiomarkersFemaleHospital MortalityHumansKaplan-Meier EstimateMaleMiddle AgedPostoperative PeriodPrognosisRetrospective StudiesSurvival RateBiomarkersProcalcitoninLiver Transplant PatientsMortalityPCTRetrospective study

Identifiers

PMID42374251
PMCPMC13579735

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.