Evidence map›Paper›PMID 42374077›Full record

ArticleScientific reports2026

Clarifying the molecular mechanisms underlying the lethal in vitro cellular effects and mild organismal phenotype of SOD1 loss.

Ying Wang, Alycia Noë, Long Truong-Ong, Siegfried Hekimi

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ying WangDepartment of Biology, McGill University, Montreal, QC, Canada.
Alycia NoëDepartment of Biology, McGill University, Montreal, QC, Canada.
Long Truong-OngDepartment of Biology, McGill University, Montreal, QC, Canada.
Siegfried HekimiDepartment of Biology, McGill University, Montreal, QC, Canada. siegfried.hekimi@mcgill.ca.

Funding

CIHR FDN-159916
6 · The paper itself

Abstract

SOD1 is the superoxide dismutase localized principally to the cytoplasm. It is found in all cell types, is extremely abundant, and highly efficient at converting superoxide (O

Indexed as

AscorbateConditional knockoutDevelopmental compensationSuperoxide dismutase 1 (SOD1)Superoxide toxicityVitamin C

Identifiers

PMID42374077
PMCPMC13612243

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.