ArticleCardiovascular and interventional radiology2026
Technically Successful Mechanical Thrombectomy for Acute Lower-Limb Ischaemia and 30-day Limb Salvage: A Single-centre Study.
Article in Cardiovascular and interventional radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo describe lesion extent, post-thrombectomy angiographic flow, and early outcome after mechanical thrombectomy for acute lower-limb ischaemia, and to assess whether angiographic technical success by Thrombo-aspiration in Peripheral Ischaemia (TIPI) grade is concordant with 30-day limb salvage. MATERIALS AND
methodsThis retrospective single-centre registry study included 69 acute lower-limb mechanical thrombectomy procedures from 100 lower-limb interventions in 2019-2025. Target segments, thrombus extent, post-thrombectomy TIPI grade, and 30-day outcomes were analysed at the procedure level. Angiographic technical success was defined as TIPI grade 2-3. The primary endpoint was 30-day limb salvage. Paired discordance was assessed using the exact McNemar test.
resultsMedian age was 71.0 years, 25/69 limbs (36.2%) had Rutherford IIb ischaemia, and multilevel thrombosis was present in 62/69 procedures (89.9%). Tibioperoneal/tibial involvement was present in 56/69 (81.2%), and pedal arch/foot involvement in 20/69 (29.0%). Post-thrombectomy TIPI grades were 0 in 1/69, 2 in 41/69, and 3 in 27/69 procedures; angiographic technical success was achieved in 68/69 (98.6%; 95% CI, 92.2-100.0). Thirty-day limb salvage was 59/69 (85.5%; 95% CI, 75.0-92.8), with a paired gap of 13.0 percentage points. Exact McNemar testing showed discordance (p = 0.0039): 9 of 10 limbs not salvaged had angiographic technical success. Distal embolization was evaluable in 66 procedures and occurred in 16/66 (24.2%); 30-day mortality was 6/69 (8.7%).
conclusionAngiographic technical success by TIPI grade 2-3 was frequent but not fully concordant with 30-day limb salvage. These findings support reporting post-thrombectomy flow and downstream perfusion rather than relying on target-segment technical success alone.
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