Evidence map›Paper›PMID 42373866›Full record

ArticleScientific reports2026

Randomized trial of a single-session digital intervention targeting emotion-related beliefs and emotion regulation.

Corey R Roos, R Kathryn McHugh, Nilofar Vafaie, Jessica Schleider, Riley McDanal, Andrew DeBenedictis, Robert Palmer, Maya John, Victoria R Votaw, Hedy Kober

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Corey R RoosDepartment of Psychiatry, Yale University School of Medicine, 1 Church Street, 7th Floor, New Haven, CT, USA. corey.roos@yale.edu.
R Kathryn McHughDivision of Alcohol and Drug Abuse, McLean Hospital, Belmont, MA, USA.
Nilofar VafaieDepartment of Psychology, Emory University, Atlanta, GA, USA.
Jessica SchleiderMedical Social Sciences, Feinberg School of Medicine, Northwestern University, Evanston, IL, USA.
Riley McDanalDepartment of Psychology, Stony Brook University, Stony Brook, NY, USA.
Andrew DeBenedictisLynch School of Education and Human Development, Boston College, Boston, MA, USA.
Robert PalmerDepartment of Psychiatry, Yale University School of Medicine, 1 Church Street, 7th Floor, New Haven, CT, USA.
Maya JohnDepartment of Psychiatry, Yale University School of Medicine, 1 Church Street, 7th Floor, New Haven, CT, USA.
Victoria R VotawDepartment of Psychiatry, Harvard Medical School, Boston, MA, USA.
Hedy KoberDepartment of Psychiatry, Yale University School of Medicine, 1 Church Street, 7th Floor, New Haven, CT, USA.

Funding

IMPLEMENTATION RESEARCH INSTITUTE FOR MENTAL HEALTH SERVICES IRI-MHSR25MH080916 · NIMH · WASHINGTON UNIVERSITY · PI Byron James Powell · 2009 to 2026
$3.7M
Regulation of Craving: Clinical Trial and Neural MechanismsR01AA029137 · NIAAA · YALE UNIVERSITY · PI KOBER, HEDY · 2021 to 2025
$3.4M
Testing Scalable, Single-Session Interventions for Adolescent Depression in the context of COVID-19DP5OD028123 · OD · STATE UNIVERSITY NEW YORK STONY BROOK · PI SCHLEIDER, JESSICA LEE · 2019 to 2023
$2.8M
Web-Based Mindfulness Treatment to Prevent Relapse to Substance UseK23AT011342 · NCCIH · YALE UNIVERSITY · PI ROOS, COREY · 2020 to 2024
$823k
Developing the Unified Protocol-Single Session Experience Platform for Adolescent Mental HealthR43MH128075 · NIMH · 3-C INSTITUTE FOR SOCIAL DEVELOPMENT · PI DEROSIER, MELISSA E., EHRENREICH-MAY, JILL · 2021 to 2021
$259k
NCCIH NIH HHS K23 AT011342NCCIH NIH HHS K23AT011342NIAAA NIH HHS R01 AA029137NIAAA NIH HHS R01AA029137NIH HHS DP5 OD028123NIMH NIH HHS R25 MH080916NIMH NIH HHS R43 MH128075
6 · The paper itself

Abstract

There is a lack of accessible and efficacious interventions for emotionally distressed adults. We developed a single-session digital intervention, called Visitor Mindset, targeting beliefs about negative emotions and awareness, clarity, and acceptance of negative emotions. We evaluated the acceptability, feasibility, and short-term efficacy of Visitor Mindset among emotionally distressed adults (n = 530). Participants were recruited via CloudResearch and randomized to Visitor Mindset or control (nature videos with relaxing music). The primary outcome was emotional distress. Secondary outcomes were functional impairment and alcoholic drinks per week. Outcomes were assessed before randomization and at 2-week follow-up. All participants randomized to Visitor Mindset completed the intervention. Acceptability ratings (e.g., perceived helpfulness) for Visitor Mindset were favorable. There was not a significant difference in changes in emotional distress between treatment conditions (d=0.13, p>.05). However, Visitor Mindset, versus control, resulted in greater reductions in functional impairment (d=0.21, p< .05) and drinks per week (d=0.21, p< .05). Improvement in acceptance and reduction in the belief negative emotions last a long time significantly mediated the effects of Visitor Mindset on emotional distress and functional impairment (p's< 0.05), but not drinks per week. Among participants with at least moderate-to-severe emotional distress, the effect of Visitor Mindset on emotional distress in this case was significant (d=0.34, p< .05), and the effect of Visitor Mindset on functional impairment was stronger (d=0.31, p< .05) in this subsample relative to the effect in the full sample. Functional impairment, but not other outcomes, demonstrated clinical significance. That is, Visitor Mindset participants were 61% more likely than control participants to change from a clinical score to a subclinical score for functional impairment. Visitor Mindset is feasible and acceptable, and may be promising for improving functioning and reducing alcohol use among emotionally distressed adults. Additionally, Visitor Mindset appears to mobilize theorized mechanisms. Future research is warranted with longer-term follow-ups.

Indexed as

Alcohol useEmotional distressEmotion regulationEmotion-related beliefsMindfulnessSingle-sessionWeb-based intervention

Identifiers

PMID42373866
PMCPMC13616734

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.