Evidence map›Paper›PMID 42373666›Full record

Trial reportScientific reports2026

The effect of amniotic membrane application on post-cesarean wound healing and cosmetic outcomes.

Yusuf Başkıran, Kazım Uçkan, İzzet Çeleğen, Fatma Başak Tanoğlu

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yusuf BaşkıranFaculty of Medicine, Department of Obstetrics and Gynecology, Istinye University, Istanbul, Turkey. yusuf.baskiran@istinye.edu.tr.
Kazım UçkanFaculty of Medicine, Department of Obstetrics and Gynecology, Van Yuzuncu Yil University, Van, Turkey.
İzzet ÇeleğenFaculty of Medicine Department of Public Health, Yuzuncu Yil University, Van, Turkey.
Fatma Başak TanoğluAcibadem Healthcare Group, Department of Obstetrics and Gynecology, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-cesarean wound complications-such as surgical site infection (SSI), dehiscence, and hypertrophic scarring-remain a challenge in obstetric surgery. We evaluated whether intraoperative autologous amniotic membrane application improves postoperative outcomes. In a single-blind, randomized controlled trial, 372 women undergoing elective cesarean section were allocated to an amniotic membrane group (n = 174) or control group (n = 198). SSI incidence was lower with amniotic membrane (4.3% vs. 10.8%; p < 0.05), and wound dehiscence was reduced (2.1% vs. 6.4%; p < 0.05). Postoperative pain scores (Visual Analog Scale) were significantly lower in the amniotic membrane group on postoperative day 1 (3.38 ± 1.36 vs. 4.05 ± 1.53; p = 0.01) and day 2 (1.25 ± 0.71 vs. 2.01 ± 0.98; p = 0.001). Clinician-rated cosmetic appearance (Modified Hollander Wound Evaluation Scale) did not differ between groups (p = 0.863), whereas patient-reported satisfaction was higher with amniotic membrane (p = 0.001). No predefined adverse events were observed. These findings suggest that amniotic membrane application may reduce wound-related complications and postoperative pain and improve patient satisfaction after cesarean delivery; confirmatory studies in broader populations are warranted.

Indexed as

AmnionCesarean SectionSurgical Wound InfectionWound HealingAdultFemaleHumansPatient SatisfactionPostoperative PainPregnancySingle-Blind MethodSurgical Wound DehiscenceTreatment OutcomeAmniotic membraneCesarean sectionPostoperative painSurgical site infectionWound healing

Identifiers

PMID42373666
PMCPMC13315581

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.