Evidence map›Paper›PMID 42373220›Full record

ArticleCancer genomics & proteomics

Deming Li, Jianan Zhou, L I Feng

Abstract read
In one paragraph

Article in Cancer genomics & proteomics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Deming LiEndoscopy Center, Minhang Hospital, Fudan University, Shanghai, P.R. China.
Jianan ZhouDepartment of Hematology, Shanghai Fifth People's Hospital, Shanghai, P.R. China.
L I FengEndoscopy Center, Minhang Hospital, Fudan University, Shanghai, P.R. China; dmli22@m.fudan.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimThe inflammatory microenvironment plays a critical role in stomach adenocarcinoma (STAD); however, the clinical relevance of inflammation-related genes remains unclear. This study aimed to identify key inflammation-related hub genes and evaluate their prognostic, immunological, and therapeutic significance in STAD. MATERIALS AND

methodsThis study integrated six transcriptomic datasets from GEO and TCGA databases to identify differentially expressed genes (DEGs) between STAD and normal tissues. Inflammation-related DEGs were enriched using the MSigDB hallmark gene set, followed by protein-protein interaction (PPI) network analysis to identify hub genes. The expression, diagnostic value, prognostic significance, immune microenvironment associations, and drug sensitivity of the key hub gene,

results

conclusion

Indexed as

AdenocarcinomaBiomarkers, TumorInflammationNADPH Oxidase 4Stomach NeoplasmsTumor MicroenvironmentGene Expression Regulation, NeoplasticHumansPrognosisProtein Interaction MapsBiomarkers, TumorNADPH Oxidase 4NOX4 protein, humanGastric cancerimmunityinflammatory responsemutationNOX4

Identifiers

PMID42373220
PMCPMC13321715

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.