Evidence map›Paper›PMID 42373191›Full record

Observational studyBMJ open2026

Outcomes of open abdominal surgery at a single-centre tertiary referral hospital in Tanzania: a prospective, observational, single-arm cohort study.

Nathan Brand, Larry Akoko, Emmanuel Obedi, Ally Mwanga, Godfrey Sama Philipo, Charles Komba, Marissa Boeck

Abstract readObservational Study
In one paragraph

Observational study in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nathan BrandDepartment of Surgery, University of California San Francisco, San Francisco, California, USA nathanrbrand@gmail.com.ORCID http://orcid.org/0000-0003-0405-3364
Larry AkokoCenter for Health Equity in Surgery and Anesthesia, Institute for Global Health Sciences, University of California, San Francisco, San Francisco, CA, USA.
Emmanuel ObediCenter for Health Equity in Surgery and Anesthesia, Institute for Global Health Sciences, University of California, San Francisco, San Francisco, CA, USA.
Ally MwangaCenter for Health Equity in Surgery and Anesthesia, Institute for Global Health Sciences, University of California, San Francisco, San Francisco, CA, USA.
Godfrey Sama PhilipoEpidemiology and Biostatistics, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania, United Republic of.
Charles KombaDepartment of Surgery, Muhimbili National Hospital, Dar es Salaam, Tanzania, United Republic of.
Marissa BoeckDepartment of Surgery, University of California San Francisco, San Francisco, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the outcomes of patients undergoing open abdominal surgery at a National Referral Hospital in Tanzania.

designA prospective, observational, single-arm cohort study.

settingDar es Salaam, Tanzania.

participantsPatients who underwent open abdominal surgery between August 2022 and July 2023 were included. Patients were enrolled if they provided informed consent to participate and were ≥18 years of age. Patients were excluded if they were lost to follow-up, were admitted outside the department of surgery or were still admitted since the index surgery at the end of the study.

main outcome measuresThe primary outcome was a composite measurement of mortality that includes patients who died during the index admission and those who died up to 30 days postdischarge. Secondary outcomes included surgical complications, unplanned readmissions, economic burden and functional outcomes. Clinically relevant factors identified a priori and with a p value of ≤0.2 in the univariable model were tested in a multivariable logistic regression to identify independent risk factors for composite mortality, with backward stepwise elimination using a statistical significance set at a p value <0.05 and 95% CI not including 1.0.

resultsOf 626 patients who had an open abdominal surgery, 555 (88.7%) met the inclusion criteria, of which 120 (21.6%) died. Of the deaths, 61 (51%) occurred during the index admission, 48 (40%) outside the hospital and 11 (9%) following unplanned readmission. Among the surviving 435 (78%) patients who participated in the 30-day follow-up, those without insurance were less likely to return to work (7.3% vs 16% insured) and had higher out-of-pocket expenses ($321 vs $82 insured).

conclusionsOpen abdominal surgery carries a composite mortality rate of 22% with almost half of deaths occurring after index hospital discharge. These findings underscore the need for routine follow-up, early complication identification and management and universal health coverage to improve outcomes, and reduce financial hardships.

Indexed as

AbdomenPostoperative ComplicationsAdultAgedFemaleHumansMaleMiddle AgedPatient ReadmissionProspective StudiesRisk FactorsTanzaniaTertiary Care CentersAdult surgeryHealth economicsSURGERYTreatment Outcome

Identifiers

PMID42373191
PMCPMC13330886

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.