ReviewDevelopmental cognitive neuroscience2026
Untangling relationships between cognitive development and child and adolescent mental health: Findings from the ABCD Study.
Review in Developmental cognitive neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adolescence marks a period of profound neurocognitive maturation, during which cognitive, neural, and biological systems dynamically interact with emerging mental health symptoms. The Adolescent Brain Cognitive Development (ABCD) Study provides a unique opportunity to examine these relationships across late childhood and adolescence using large-scale, longitudinal, multimodal data. This review synthesizes research using the ABCD dataset to investigate links between cognitive processes and mental health across five longitudinal assessment waves (ages 9-14), covering externalizing and internalizing symptoms, depression, anxiety, ADHD, psychotic-like experiences, obsessive-compulsive symptoms, suicidality, substance use, and autism spectrum disorder. We summarize evidence linking core cognitive domains-including executive function, working memory, attention, and processing speed-to mental health symptoms, and highlight studies integrating neuroimaging and genetic data to elucidate underlying mechanisms. Findings revealed common and distinct cognitive impairment patterns across conditions: executive function and working memory impairments were consistently associated with externalizing symptoms, ADHD, and disruptive behavior disorders, while internalizing relationships were more heterogeneous. Psychotic-like experiences had consistent and persistent cognitive associations, with stronger longitudinal coupling between cognitive trajectories and symptom progression, compared to other symptom domains. Data-driven approaches were commonly used, and neuroimaging and genetic findings identified converging mechanisms within some disorders. Effect sizes were predominantly small, as expected in a large community sample, yet consistent replication across analytic approaches suggests these estimates reflect population-level relationships. Collectively, findings from the ABCD Study position cognition as a key component within multimodal developmental models of psychiatric risk, with implications for identifying early cognitive markers that may inform targeted intervention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.