ArticleArchives of oral biology2026
Impact of lifestyle factors on salivary nitrite and nitrate concentrations in overweight/obese individuals.
Article in Archives of oral biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Corrections and comments
- Erratum issued
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5 authors.
Funding
Abstract
objectiveThis study aimed to evaluate the association of lifestyle factors (smoking, physical activity, consumption of sugar-sweetened beverages and alcohol, and oral hygiene practices) with salivary nitrite and nitrate concentrations.
designThis cross-sectional study included 1076 overweight/obese adults (aged 40-65 years) from the San Juan Overweight Adult Longitudinal Study (SOALS). Salivary nitrite and nitrate concentrations were measured using Eicom's ENO-30. Associations between lifestyle factors and salivary nitrite/nitrate concentrations were evaluated using Wilcoxon rank-sum test, Kruskal-Wallis with Dunn's test, Spearman correlation, and Gamma regression controlling for age, sex, metabolic syndrome, and bleeding on probing.
resultsSmoking (former and current), sugar-sweetened beverage consumption, and plaque index were associated with lower salivary nitrite or nitrate concentrations (p < 0.001-0.048). Twice-daily brushing (p = 0.025) and daily flossing (p = 0.015) were associated with higher salivary nitrite compared to less frequent practices. Over-the-counter mouthwash use (≥2 times daily) was positively associated with nitrate concentrations (p = 0.028). No significant associations were observed for alcohol consumption and physical activity.
conclusionsOptimal oral hygiene practices are positively associated with salivary nitrate and nitrite concentrations, while smoking and sugar-sweetened beverages consumption show negative associations. This highlights their potential relevance for oral and cardiometabolic health in individuals with overweight or obese.
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