Evidence map›Paper›PMID 42371463›Full record

ArticleCureus2026

Long-Term Outpatient Epidural Analgesia in Advanced Colorectal Adenocarcinoma: A Case Report.

Ricardo Toipa Lopes, Noélia Carrillo-Alfonso, Cláudia Martins, Ana Lares

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ricardo Toipa LopesAnesthesiology, Centro Hospitalar Universitário do Algarve, Faro, PRT.
Noélia Carrillo-AlfonsoAnesthesiology, Centro Hospitalar Universitário do Algarve, Faro, PRT.
Cláudia MartinsAnesthesiology, Centro Hospitalar Universitário do Algarve, Faro, PRT.
Ana LaresAnesthesiology, Centro Hospitalar Universitário do Algarve, Faro, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pain is highly prevalent among patients with advanced cancer and often remains refractory to optimized systemic analgesia. When opioid therapy fails or causes intolerable side effects, interventional techniques may offer improved symptom control and quality of life. We report the case of a 73-year-old man with metastatic colorectal carcinoma who presented with lumbar plexus compression and severe refractory gluteal pain secondary to sacral tumor invasion and infiltration of the musculotendinous structures. Despite optimized systemic analgesia, the patient continued to experience pain ≥7/10, accompanied by a progressive decline in functional status. An epidural catheter was placed and connected to a patient-controlled epidural analgesia system delivering ropivacaine. This intervention enabled home-based management with scheduled follow-up. The patient had effective pain relief, allowing for the recovery of functional capacity. Dose adjustments were made as the disease progressed. The patient remained at home with sustained analgesic benefit until his death due to cancer progression. This case supports the role of outpatient epidural analgesia as an effective and safe palliative option for selected terminal cancer patients with uncontrolled pain, particularly when mobility and quality of life can be preserved.

Indexed as

advanced colorectal cancerepidural analgesiaoutpatient pain managementpalliative carerefractory cancer pain

Identifiers

PMID42371463
PMCPMC13310536

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.