Evidence map›Paper›PMID 42371297›Full record

ArticleThe Journal of the Egyptian Public Health Association2026

Integrated evaluation of environmental monitoring, rheumatoid arthritis biomarkers, and genetic variants in textile dyeing workers.

Amal Saad-Hussein, Eman M Shahy, Mona M Taha, Gehan Moubarz, Heba Mahdy-Abdallah, Lamia S Ellaithy, Inas A Saleh, Atef M F Mohammed

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Article in The Journal of the Egyptian Public Health Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Amal Saad-HusseinEnvironmental & Occupational Medicine Department, Environment & Climate Change Research Institute, National Research Centre, Cairo, Egypt.
Eman M ShahyEnvironmental & Occupational Medicine Department, Environment & Climate Change Research Institute, National Research Centre, Cairo, Egypt.
Mona M TahaEnvironmental & Occupational Medicine Department, Environment & Climate Change Research Institute, National Research Centre, Cairo, Egypt. monataha45@yahoo.com.
Gehan MoubarzEnvironmental & Occupational Medicine Department, Environment & Climate Change Research Institute, National Research Centre, Cairo, Egypt.
Heba Mahdy-AbdallahEnvironmental & Occupational Medicine Department, Environment & Climate Change Research Institute, National Research Centre, Cairo, Egypt.
Lamia S EllaithyEnvironmental & Occupational Medicine Department, Environment & Climate Change Research Institute, National Research Centre, Cairo, Egypt.
Inas A SalehAir Pollution Department, Environment & Climate Change Research Institute, National Research Centre, Cairo, Egypt.
Atef M F MohammedAir Pollution Department, Environment & Climate Change Research Institute, National Research Centre, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWorkers in the textile dyeing industry are occupationally exposed to high concentrations of particulates and volatile organic compounds (VOCs). This work aimed to study the environment-gene interaction as a risk factor for rheumatoid arthritis in textile dyeing workers.

methodsThis cross-sectional comparative study included 140 exposed male workers and 130 matched control workers. Air monitoring of chemical air pollutants in the workplace was conducted for 12 months. Estimation of anti-CCP, CRP, RF, ANA antibodies, and the CYP2E1 and GST genes polymorphisms was studied in both groups.

resultsHigh air concentrations of PM

conclusionThe environment-gene interaction of the elevation of PM10 and VOCs concentrations in the dyeing section, with the CYP2E1 (C2/C2 mutant genotype) and the GST (M1 polymorphism), could be a risk factor for RF elevation in the workers from the dyeing section compared to the other two sections. The key recommendations include improving environmental control in the workplace, ensuring the proper use of personal protective equipment (PPE), conducting pre-employment screening for genetic susceptibility through genetic counseling for CYP2E1 and GST polymorphisms, and providing regular medical follow-up for workers carrying the CYP2E1 (C2/C2) genotype and the GST (M1) allele.

Indexed as

Air particulatesAir volatile organic compoundsCYP2E1 gene polymorphismGST gene polymorphismRheumatoid arthritis biomarkersTextile dyeing workers

Identifiers

PMID42371297
PMCPMC13315032

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.