Evidence map›Paper›PMID 42371134›Full record

ArticlePediatric surgery international2026

Lobectomy versus lung-sparing resection for congenital pulmonary airway malformation (CPAM): a single-center comparative study.

Irene Paraboschi, Ugo Maria Pierucci, Carlotta Ardenghi, Michela Marinaro, Michele Ceresola, Eleonora Durante, Sara Baroni, Salvatore Zirpoli, Michele Ghezzi, Francesca Izzo and 3 more

Abstract readComparative Study
In one paragraph

Article in Pediatric surgery international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Irene ParaboschiDepartment of Biomedical and Clinical Science, University of Milano, Milan, Italy. irene.paraboschi@unimi.it.
Ugo Maria PierucciDepartment of Pediatric Surgery, "Vittore Buzzi" Children's Hospital, Milan, Italy.
Carlotta ArdenghiDepartment of Pediatric Surgery, "Vittore Buzzi" Children's Hospital, Milan, Italy.
Michela MarinaroDepartment of Pediatric Surgery, "Vittore Buzzi" Children's Hospital, Milan, Italy.
Michele CeresolaDepartment of Pediatric Surgery, "Vittore Buzzi" Children's Hospital, Milan, Italy.
Eleonora DuranteDepartment of Pediatric Surgery, "Vittore Buzzi" Children's Hospital, Milan, Italy.
Sara BaroniDepartment of Pediatric Surgery, "Vittore Buzzi" Children's Hospital, Milan, Italy.
Salvatore ZirpoliPediatric Radiology Unit, "Vittore Buzzi" Children's Hospital, Milan, Italy.
Michele GhezziPediatric Department, "Vittore Buzzi" Children's Hospital, Milano, Italy.
Francesca IzzoAnesthesia and Intensive Care Unit, "Vittore Buzzi" Children's Hospital, Milan, Italy.
Anna MandelliAnesthesia and Intensive Care Unit, "Vittore Buzzi" Children's Hospital, Milan, Italy.
Sara CostanzoDepartment of Pediatric Surgery, "Vittore Buzzi" Children's Hospital, Milan, Italy.
Gloria PelizzoDepartment of Biomedical and Clinical Science, University of Milano, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo compare perioperative and long-term outcomes of lobectomy versus lung-sparing resection in children undergoing surgery for congenital pulmonary airway malformation (CPAM).

methodsA retrospective single-center study was conducted including children who underwent primary surgical resection for postnatally confirmed CPAM between 2005 and 2024. Patients with other congenital lung lesions, bilateral disease, syndromic conditions, or incomplete data were excluded. Perioperative variables, postoperative outcomes, redo surgery, and chest wall anomalies were compared between lobectomy and lung-sparing resections. Continuous variables were analyzed using the Mann-Whitney U test and categorical variables using Fisher's exact test.

resultsThirty-one children were included (22 lobectomies, 9 lung-sparing resections), with a median age at surgery of 8 months. Operative time (207 vs. 149 min, p = 0.0425) and anesthesia time (371 vs. 230 min, p = 0.0171) were significantly longer for lobectomy. Intraoperative complications occurred in 10% of patients, with no significant difference between groups. Postoperative complications were less frequent after lobectomy (19% vs. 44%), although not statistically significant (p = 0.1954). Redo surgery was required exclusively after lung-sparing resections (33% vs. 0%, p = 0.0207). Length of hospital stay and NICU/PICU stay were comparable. At a median follow-up of 71 months, chest wall deformities were observed less often after lobectomy (22% vs. 43%, p = 0.3554).

conclusionsDespite longer operative and anesthesia times, lobectomy provided more definitive disease control, with a significantly lower need for redo surgery compared with lung-sparing resection. Lobectomy remains the most reliable surgical option for CPAM in children, while lung-sparing approaches should be reserved for carefully selected cases.

Indexed as

Cystic Adenomatoid Malformation of Lung, CongenitalOrgan Sparing TreatmentsPneumonectomyChild, PreschoolFemaleHumansInfantMalePostoperative ComplicationsRetrospective StudiesTreatment OutcomeCompensatory activationDeltoid muscleReal-time tissue elastographyRemaining rotator cuff musclesRotator cuff tears

Identifiers

PMID42371134
PMCPMC13314818

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