SynthesisNeuroradiology2026
Magnetic resonance imaging use in pediatric deep brain stimulation: a systematic review and call for standardization.
Synthesis in Neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Who cites it
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeDeep brain stimulation (DBS) is a well-established therapy for adult neurological disorders, most commonly Parkinson's disease, and is increasingly being explored for medically refractory conditions in the pediatric population. Magnetic Resonance Imaging (MRI) is essential for DBS safety and efficacy through precise surgical targeting and trajectory planning, yet MRI protocols and reporting vary substantially and are constrained by pediatric-specific considerations. We aimed to systematically characterize MRI use and reporting practices in pediatric DBS studies and clinical trial registries.
methodsWe systematically reviewed the published literature and the clinical trials registry to characterize MRI use in pediatric patients undergoing DBS, identify common imaging practices, and evaluate reporting of MRI sequence parameters (e.g., TR, TE).
resultsPreoperative MRI was primarily used for anatomical targeting and surgical planning. Most studies used 1.5T scanners (86%) versus 3T (14%), with T1-weighted (54%) and T2-weighted (53%) sequences most common. Despite MRI's ubiquity, 78% of studies did not report sequence parameters. However, only 4% were published in imaging-related specialty journals, which may explain the limited methodological detail. CLINICALTRIALS: gov data reflected the same pattern, where DBS trials that mention imaging, rarely specify sequences or acquisition parameters.
conclusionHeterogeneous MRI protocols and frequent under-reporting limit reproducibility and comparison of targeting approaches across pediatric DBS studies. We advocate for standardized MRI reporting guidelines to strengthen methodological rigour and accelerate collaborative progress in pediatric DBS research.
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