Evidence map›Paper›PMID 42371006›Full record

ArticleVirchows Archiv : an international journal of pathology2026

Mismatch repair protein deficiency (MMRd) and high microsatellite instability (MSI-H) in gastrointestinal stromal tumour (GIST) - a case report and review of the literature of this exceedingly rare phenotype.

Timothy Kwang Yong Tay, Gek San Tan, Say Hwee Lee, Chee Seng Chan, Jeremy Wee Kiat Ng, Eileen Xueqin Chen, Amos Zhi En Tay, Urera Mariana Quesada, Wui Seng Khoo, Tony Kiat Hon Lim

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Article in Virchows Archiv : an international journal of pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Timothy Kwang Yong TayDuke-NUS Medical School, Singapore, Singapore. timothy.tay.k.y@singhealth.com.sg.ORCID http://orcid.org/0000-0001-8592-5018
Gek San TanDepartment of Anatomical Pathology, Singapore General Hospital, 20 College Road, Academia, Diagnostic Tower Level 10, Singapore, 169856, Singapore.
Say Hwee LeeDepartment of Anatomical Pathology, Singapore General Hospital, 20 College Road, Academia, Diagnostic Tower Level 10, Singapore, 169856, Singapore.
Chee Seng ChanDepartment of Anatomical Pathology, Singapore General Hospital, 20 College Road, Academia, Diagnostic Tower Level 10, Singapore, 169856, Singapore.
Jeremy Wee Kiat NgDuke-NUS Medical School, Singapore, Singapore.
Eileen Xueqin ChenDepartment of Microbiology, Singapore General Hospital, Singapore, Singapore.
Amos Zhi En TayDuke-NUS Medical School, Singapore, Singapore.
Urera Mariana QuesadaDepartment of Anatomical Pathology, Singapore General Hospital, 20 College Road, Academia, Diagnostic Tower Level 10, Singapore, 169856, Singapore.
Wui Seng KhooDepartment of Anatomical Pathology, Singapore General Hospital, 20 College Road, Academia, Diagnostic Tower Level 10, Singapore, 169856, Singapore.
Tony Kiat Hon LimDuke-NUS Medical School, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of mismatch repair protein deficient (MMRd) and high microsatellite instability (MSI-H) GIST that is exceedingly rare. The patient is an elderly male who presented with abdominal discomfort and poor appetite. Investigations revealed a gastric GIST (CD117 and DOG1 positive, SDH expression retained), spindle cell type, 22 cm in size with 23 mitoses per 5mm

Indexed as

Gastrointestinal stromal tumourMicrosatellite instabilityMismatch repairTumour mutational burden

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.