Evidence map›Paper›PMID 42370792›Full record

ArticleJournal of medicinal chemistry2026

Discovery of

Austin Chen, Christopher Baccei, Jill Baccei, Alexander Broadhead, Kym I Lorrain, Michael M Poon, Jeffrey Roppe, Thomas O Schrader, Karin J Stebbins, Lino Valdez and 2 more

Abstract read
In one paragraph

Article in Journal of medicinal chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Austin ChenContineum Therapeutics, 3565 General Atomics Court, Suite 200, San Diego, California 92121, United States.ORCID 0009-0005-1749-5622
Christopher BacceiContineum Therapeutics, 3565 General Atomics Court, Suite 200, San Diego, California 92121, United States.
Jill BacceiContineum Therapeutics, 3565 General Atomics Court, Suite 200, San Diego, California 92121, United States.
Alexander BroadheadContineum Therapeutics, 3565 General Atomics Court, Suite 200, San Diego, California 92121, United States.
Kym I LorrainContineum Therapeutics, 3565 General Atomics Court, Suite 200, San Diego, California 92121, United States.
Michael M PoonContineum Therapeutics, 3565 General Atomics Court, Suite 200, San Diego, California 92121, United States.
Jeffrey RoppeContineum Therapeutics, 3565 General Atomics Court, Suite 200, San Diego, California 92121, United States.
Thomas O SchraderContineum Therapeutics, 3565 General Atomics Court, Suite 200, San Diego, California 92121, United States.ORCID 0000-0003-3468-9566
Karin J StebbinsContineum Therapeutics, 3565 General Atomics Court, Suite 200, San Diego, California 92121, United States.
Lino ValdezContineum Therapeutics, 3565 General Atomics Court, Suite 200, San Diego, California 92121, United States.
Yifeng XiongContineum Therapeutics, 3565 General Atomics Court, Suite 200, San Diego, California 92121, United States.
Daniel S LorrainContineum Therapeutics, 3565 General Atomics Court, Suite 200, San Diego, California 92121, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe the discovery and characterization of

Indexed as

BrainNeuroinflammatory DiseasesReceptors, Lysophosphatidic AcidUreaAnimalsBlood-Brain BarrierClinical Trials, Phase I as TopicDrug DiscoveryHumansMaleRandomized Controlled Trials as TopicRatsRats, Sprague-DawleyStructure-Activity RelationshipSwineSwine, MiniatureReceptors, Lysophosphatidic AcidUrea

Identifiers

PMID42370792
PMCPMC13370876

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.