Evidence map›Paper›PMID 42370758›Full record

ReviewCPT: pharmacometrics & systems pharmacology2026

A Narrative Review of Artificial Intelligence for Drug Repurposing: Lessons From COVID-19 and Oncology (2020-2025).

Alaba Bukola Ogungbite, Malusi Sibiya

Abstract readReview
In one paragraph

Review in CPT: pharmacometrics & systems pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alaba Bukola OgungbiteDepartment of Computer Science, University of South Africa, Florida, South Africa.ORCID https://orcid.org/0009-0002-8546-3233
Malusi SibiyaDepartment of Computer Science, University of South Africa, Florida, South Africa.ORCID https://orcid.org/0000-0001-5617-768X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug repurposing presents a cost-effective and time-efficient strategy to identify new therapeutic applications for existing drugs. Recent advances in artificial intelligence, including machine learning, deep learning, knowledge graphs, and natural language processing, have revolutionized this field by enabling automated discovery of drug-disease associations. This review examines the role of artificial intelligence in drug repurposing, drawing insights from two critical case areas: Coronavirus disease 2019 and oncology. We explore current trends, methodological frameworks, and technological innovations in artificial intelligence-driven drug repurposing, as well as challenges and emerging future directions. The findings of this paper underscore the transformative potential of artificial intelligence in biomedical research and justify its continued integration in pharmaceutical pipelines.

Indexed as

Artificial IntelligenceCOVID-19 Drug TreatmentDrug RepositioningNeoplasmsAntineoplastic AgentsCOVID-19Deep LearningHumansMachine LearningMedical OncologyNatural Language ProcessingSARS-CoV-2Antineoplastic Agentsartificial intelligenceCOVID‐19deep learningdrug repurposingknowledge graphsmachine learningnatural language processingoncology

Identifiers

PMID42370758
PMCPMC13312802

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.