ArticleMicrobiology spectrum2026
Fluoroquinolone-resistant
Kevin Kariuki, Kirkby D Tickell, Collins Kigen, James Wachira, Polycarp Mogeni, Doreen Rwigi, Cecilia Mbae, Kelvin Kering, Benson Singa, Judd L Walson and 3 more
Abstract read
In one paragraphArticle in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
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0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
13 authors.
Kirkby D TickellDepartment of Global Health, University of Washington, Seattle, Washington, USA.
Collins KigenMicrobiology Hub, Walter Reed Army Institute of Research-Africa, Kericho, Kenya.
James WachiraMicrobiology Hub, Walter Reed Army Institute of Research-Africa, Kericho, Kenya.
Polycarp MogeniCentre for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.
Doreen RwigiCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Cecilia MbaeCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Benson SingaCentre for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.
Judd L WalsonThe Childhood Acute Illness & Nutrition (CHAIN) Network, Nairobi, Kenya.
Samuel KariukiCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Ferric C FangDepartment of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, Washington, USA.ORCID 0000-0002-3243-110X Funding
The role of enteric pathogens and antimicrobial resistance in driving clinical and nutritional deterioration, and azithromycin's potential effect, among children discharged from hospital in KenyaR01AI150978 · NIAID · UNIVERSITY OF WASHINGTON · PI PAVLINAC, PATRICIA · 2020 to 2024
$3.7MNational Institute of Allergy and Infectious Diseases 1R01AI150978NIAID NIH HHS R01 AI150978
6 · The paper itselfAbstract
We report on five clinical fluoroquinolone-resistant IMPORTANCE: Fluoroquinolones remain critical antibiotics for the treatment of bacterial infections in low- and middle-income countries. The increasing prevalence of resistance threatens the effectiveness of these agents. This report describes the detection of a quinolone efflux pump (
Indexed as
Anti-Bacterial AgentsEscherichia coliEscherichia coli InfectionsEscherichia coli ProteinsFluoroquinolonesMembrane Transport ProteinsChild, PreschoolDrug Resistance, BacterialDrug Resistance, Multiple, BacterialFecesHumansKenyaMicrobial Sensitivity TestsWhole Genome SequencingAnti-Bacterial AgentsEscherichia coli ProteinsFluoroquinolonesMembrane Transport ProteinsQepA protein, E colichildrenEscherichia colifluoroquinolonesKenyaquinolone efflux pump
Identifiers
PMID42370683
PMCPMC13435699
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