Evidence map›Paper›PMID 42370213›Full record

ArticleNMC case report journal2026

Intraosseous Endodermal Cyst in Frontal Convexity Bone: A Case Report and Literature Review.

Hideki Kashiwagi, Naokado Ikeda, Hironori Yamada, Akihiro Kambara, Masao Fukumura, Ryokichi Yagi, Ryo Hiramatsu, Masahiro Kameda, Naosuke Nonoguchi, Motomasa Furuse and 4 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in NMC case report journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hideki KashiwagiDepartment of Neurosurgery, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.
Naokado IkedaDepartment of Neurosurgery, Takeda General Hospital, Fushimi, Kyoto, Japan.
Hironori YamadaDepartment of Neurosurgery, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.
Akihiro KambaraDepartment of Neurosurgery, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.
Masao FukumuraDepartment of Neurosurgery, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.
Ryokichi YagiDepartment of Neurosurgery, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.
Ryo HiramatsuDepartment of Neurosurgery, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.
Masahiro KamedaDepartment of Neurosurgery, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.
Naosuke NonoguchiDepartment of Neurosurgery, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.
Motomasa FuruseDepartment of Neurosurgery, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.
Shinji KawabataDepartment of Neurosurgery, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.
Toshihiro TakamiDepartment of Neurosurgery, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.
Masahiro KawanishiDepartment of Neurosurgery, Takeda General Hospital, Fushimi, Kyoto, Japan.
Masahiko WanibuchiDepartment of Neurosurgery, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endodermal cysts typically occur in intradural regions of the ventral spine or posterior cranial fossa. However, they are rarely found in supratentorial regions, especially within the frontal bone. Here, we report a rare case of an intraosseous endodermal cyst in the frontal convexity and discuss its potential pathogenesis in this unusual location. A 54-year-old woman presented with a gradually enlarging, soft, elastic mass in the left frontal region. Neurological abnormalities were not observed. Computed tomography revealed a cystic lesion within the left frontal bone, associated with a bulging contour. The cyst contents appeared hyperintense on T1-weighted magnetic resonance and showed a hypointense component on T2-weighted magnetic resonance imaging. The cyst wall was not enhanced with gadolinium. The cyst and its mucinous content were completely excised from the frontal bone. Intraoperatively, the cyst wall was completely separated from the frontal sinus by a thin bony structure. Histopathological examination revealed that the cyst wall consisted of inflammatory granulation tissue with a ciliated columnar epithelium, consistent with a diagnosis of endodermal cyst. Although the pathogenesis of supratentorial endodermal cysts remains unclear, the location of the cyst in the frontal convexity, as opposed to the anterior cranial base, may suggest a distinct pathogenesis for each endodermal cyst in terms of embryological aspects.

Indexed as

endodermal cystendodermal-neural crest adhesionfrontal bone

Identifiers

PMID42370213
PMCPMC13293710

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.