Evidence map›Paper›PMID 42370194›Full record

ReviewTheranostics2026

Sonogenetics for precision medicine: from molecular toolkit to clinical translation.

Xinrui Yu, Min Pu, Ruoli Wang, Haitao Ran

Abstract readReview
In one paragraph

Review in Theranostics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Micro/Nanoscale Acoustic Manipulation: From Particle Control to Autonomous Microswimmers.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xinrui YuDepartment of Ultrasound, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Min PuDepartment of Ultrasound, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Ruoli WangDepartment of Neurosurgery, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
Haitao RanDepartment of Ultrasound, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sonogenetics is an emerging technology for precise biological modulation. It utilizes ultrasound waves for remote, noninvasive, and spatiotemporally precise functional intervention in target cells genetically engineered for acoustic sensitivity. This review systematically summarizes the three core components comprising sonogenetics: sound-responsive agents for modulating cellular functions, highly efficient vectors for targeted gene delivery, and ultrasound emitters with optimized parameters. Furthermore, we delineate optimization strategies for these components and propose a standardized workflow for sonogenetic operations. This review proposes strategies to accelerate the transformation process of sonogenetics by analyzing current limitations in regulatory efficiency and clinical safety. Finally, this review discusses the existing technical challenges and transformation bottlenecks, and points out the promising directions of future research.

Indexed as

Precision MedicineUltrasonic WavesAnimalsGenetic TherapyGene Transfer TechniquesHumansMicrobubblesTranslational Research, Biomedicalmechanosensitive ion channelsmicrobubblesprecision medicinesonogeneticstargeted gene delivery

Identifiers

PMID42370194
PMCPMC13294989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.