ArticleTheranostics2026
Bone-Targeting Microspheres Enable Sustained Release of CD301b
Article in Theranostics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
11 authors.
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Abstract
Rationale: Large bone defects often exceed the body's intrinsic capacity for self-repair. Successful bone healing depends on a coordinated immune transition alongside tightly coupled angiogenesis and osteogenesis, in which macrophages play a key regulatory role. Therefore, ideal bone-regenerative materials should integrate immunomodulatory, pro-angiogenic, and osteogenic functions. Methods and Results: Small extracellular vesicles (sEVs) from CD301b Conclusion: This study not only overcomes key limitations of conventional sEVs therapies such as poor retention and instability, but also provides an innovative "targeted localization, intelligent release, and multifunctional synergy" strategy, offering a minimally invasive and highly effective therapeutic platform for bone repair.
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