ArticleIndian journal of anaesthesia2026
The role of the pericapsular nerve group block in early mobilisation and functional recovery after total hip arthroplasty: A systematic review and meta-analysis.
Article in Indian journal of anaesthesia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
Background and Aims: This systematic review and meta-analysis evaluated the motor-sparing pericapsular nerve group (PENG) block's effect on early mobilisation and functional recovery outcomes following total hip arthroplasty (THA). Methods: We searched MEDLINE, Web of Science, EMBASE, the Cochrane Library, ClinicalTrials.gov, and International Clinical Trials Registry Platform (ICTRP) up to 31 May 2025 for randomised controlled trials (RCTs) comparing PENG block with non-PENG analgesic strategies in adult THA patients. The primary outcome was time to first mobilisation. Secondary outcomes included Quality of Recovery (QoR) scores, quadriceps strength, hip range of motion, dynamic pain scores, patient satisfaction, and length of hospital stay. Risk of bias was assessed using the RoB 2 tool. Evidence certainty was evaluated using the GRADE (Grading of Recommendations Assessment, Development and Evaluation) framework. Meta-analyses were conducted using random-effects models. Results: Twenty-six RCTs involving 2208 patients were included. PENG block reduced time to first mobilisation [mean difference (MD), -2.68 h; 95% confidence interval (CI) -3.84 to -1.53; Conclusion: In this synthesis of RCTs through May 2025, compared with non-PENG analgesic strategies, the PENG block was associated with earlier time to first mobilisation after THA and improvements in some early recovery outcomes, including quadriceps strength on POD 1, hip range of motion, patient satisfaction, and length of stay. Further large, standardised trials are needed to validate these findings and define their clinical significance.
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