ArticleIndian journal of anaesthesia2026
Effect of sugammadex versus neostigmine/glycopyrrolate combination on peak expiratory flow rates in adult patients undergoing laparoscopic surgery.
Article in Indian journal of anaesthesia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Sugammadex in India: Still on the runway, cleared for take-off, grounded by economic constraints….Indian journal of anaesthesia · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Residual neuromuscular blockade impacts peak expiratory flow rate (PEFR). The primary aim of this study was to compare post-extubation PEFR in adults undergoing laparoscopic cholecystectomy when neuromuscular blockade was reversed by either neostigmine or sugammadex. Methods: Patients aged 18-60 years were randomised into two equal groups of 43 each based on the reversal agent used - sugammadex versus neostigmine. Pre- and post-operative PEFRs were recorded using a handheld flow-type spirometer. Percentage reduction in forced expiratory volume in first second (FEV1), forced vital capacity (FVC), and FEV1/FVC were calculated. Adverse events and recovery scores were compared between the two groups. Results: The post-operative PEFR with sugammadex was 336.88 ± 65.94 L/min, compared to 293.93 ± 43.76 L/min with neostigmine. The mean difference was statistically significant {42.95 L/min [95% confidence interval (CI): 18.95-66.95 L/min], Conclusion: Reversal of neuromuscular blockade with sugammadex is associated with higher post-operative values of PEFR when compared with neostigmine. Higher values of PEFR and FEV1, FVC, and FEV
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