Efficacy of previous failure on subsequent procedural outcomes of chronic total occlusion percutaneous coronary intervention: A systematic review and meta-analysis.

Weiqiang Sun, Ailing Wu, Can Luo

Abstract readReview

In one paragraph

Review in Pakistan journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Weiqiang SunWeiqiang Sun, Department of Cardiovascular, Changxing County People's Hospital, Huzhou, Zhejiang Province 313100, P.R. China.

Ailing WuAiling Wu, Department of Electrocardiogram Room, Changxing County People's Hospital, Huzhou, Zhejiang Province 313100, P.R. China.

Can LuoCan Luo, Department of Cardiovascular, Changxing County People's Hospital, Huzhou, Zhejiang Province 313100, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The current study aimed to review evidence on the effects of prior failed percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) on subsequent reattempted procedures. Methodology: Studies published on the databases of PubMed, Embase, Scopus, and Web of Science comparing outcomes of prior failed CTO-PCI with first-attempt CTO-PCI were included. Random-effects meta-analysis was conducted for baseline characteristics, success rates, and complications. Results: Six studies were included with 15,803 patients of which 3248 (20.6%) had prior failed PCI for CTO. Patients with prior failed CTO-PCI had significantly lower age, higher Japanese-CTO scores, higher incidence of tortuous vessels, increased contrast volume, and higher fluoroscopy time. The retrograde approach was more frequently used in prior failed cases. Meta-analysis showed that procedural (OR: 0.50 95% CI: 0.32, 0.77 I Conclusions: Evidence suggest that cases with prior failed CTO-PCI may have significantly lower procedural and technical success rates as compared to those undergoing first-attempt CTO-PCI. There may be no difference in the risk of complications between the two groups. High heterogeneity precludes strong conclusions. Further studies are needed to improve the quality of evidence.

Indexed as

Chronic total occlusionComplicationsCoronary artery diseasePercutaneous coronary intervention

Identifiers

PMID42369959

DOI10.12669/pjms.42.6.16250

PMCPMC13309889

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.