ArticlePakistan journal of medical sciences2026
A study of Tuna (Katsuwonus pelamis) Nugget Effects on Cardiometabolic Risk Factors in Ischemic Cardiomyopathy at a Public Hospital in Lahore.
Article in Pakistan journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: To evaluate the effects of selenium-enriched tuna (Katsuwonus pelamis) nuggets on anthropometric, metabolic, and inflammatory risk factors in ICM patients in Pakistan. Methodology: A 12 weeks randomized controlled intervention study was conducted in Lahore, Pakistan from May 2025 - July 2025, 120 ICM patients were assigned to either a tuna nugget intervention group (n = 60) or a control group receiving standard dietary care (n = 60). The developed tuna nuggets were high in protein (31.93%), low in fat (1.75%), and enriched with selenium and antioxidants. Anthropometric measures, fasting glucose, lipid profile, and inflammatory markers (hs-CRP) were assessed at baseline and post-intervention. Mediation analyses evaluated the role of nutrient intake on cardiometabolic outcomes. Results: The intervention group showed significant im-provements compared to controls: weight (-1.8 kg, P = 0.034), BMI (-0.7 kg/m Conclusions: Selenium-enriched tuna nuggets are a safe, palatable, and nutritionally effective dietary strategy to improve anthropometric, metabolic, and inflammatory risk factors in ICM patients. Functional food interventions like this offer a practical adjunct to conventional therapy, addressing cardiometabolic risk through targeted nutrient enhancement. Future long-term trials are warranted to evaluate sustained clinical benefits.
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