Evidence map›Paper›PMID 42369861›Full record

ArticleCase reports in hematology2026

Molecular Relapse After a Second Treatment-Free Remission Attempt Following Asciminib in Chronic Myeloid Leukemia: A Case Report.

Nobue Sato, Ryo Yoshimaru, Yong-Mei Guo, Hirotaka Nakamura, Kensuke Matsuda, Yosuke Minami, Junichiro Yuda

Abstract read
In one paragraph

Article in Case reports in hematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nobue SatoDepartment of Pharmacy, National Cancer Center Hospital East, Kashiwa, Japan, ncc.go.jp.
Ryo YoshimaruDepartment of Hematology and Oncology, National Cancer Center Hospital East, Kashiwa, Japan, ncc.go.jp.
Yong-Mei GuoDepartment of Hematology and Oncology, National Cancer Center Hospital East, Kashiwa, Japan, ncc.go.jp.
Hirotaka NakamuraDepartment of Hematology and Oncology, National Cancer Center Hospital East, Kashiwa, Japan, ncc.go.jp.
Kensuke MatsudaDepartment of Hematology and Oncology, National Cancer Center Hospital East, Kashiwa, Japan, ncc.go.jp.
Yosuke MinamiDepartment of Hematology and Oncology, National Cancer Center Hospital East, Kashiwa, Japan, ncc.go.jp.
Junichiro YudaDepartment of Hematology and Oncology, National Cancer Center Hospital East, Kashiwa, Japan, ncc.go.jp.ORCID https://orcid.org/0000-0002-4908-1636

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment-free remission (TFR) has become an important therapeutic goal in chronic myeloid leukemia (CML). Although the outcomes of TFR following adenosine triphosphate (ATP)-competitive tyrosine kinase inhibitors (TKIs) have been established, data on TFR after asciminib discontinuation remain limited. In this study, we report the case of a man in his 60s with chronic-phase CML who experienced molecular relapse 8 months after a second TFR attempt following asciminib treatment. The patient was diagnosed with CML approximately 15 years earlier and achieved deep molecular response 4.5 (MR4.5), representing a 4.5-log reduction in

Indexed as

asciminibcase reportchronic myeloid leukemiamolecular relapsetreatment-free remissiontyrosine kinase inhibitors

Identifiers

PMID42369861
PMCPMC13309912

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.