ArticleInternational journal of women's health2026
Differential Analysis of Factors Associated with Vaginal Lesions in Women of Different Age Groups.
Article in International journal of women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To investigate differences in factors associated with vaginal intraepithelial neoplasia (presence/absence and grade) such as HPV, TCT results, and concurrent lesions across age groups, supporting precise prevention and screening strategies. Methods: A retrospective study included 212 patients undergoing colposcopy and vaginal biopsy (2020-2024), grouped as <50 years (n=88) and ≥50 years (n=124). Chi-square tests or Fisher's exact test were used to compare categorical variables between groups and to analyze associations between VaIN presence and clinical factors within each age group. Spearman rank correlation was used to evaluate the correlation between VaIN grade (ordinal) and ordinal clinical factors (eg, TCT result grade, grade of previous/concurrent cervical or vulvar lesions). Results: Age <50 years was significantly associated with VaIN occurrence (P<0.05). In the ≥50 years group, TCT results more often indicated high-grade lesions (P<0.05). Within the <50 years group, VaIN presence/grade showed no significant association with HPV, TCT, concurrent cervical/vulvar lesions, or lesion history. In the group aged ≥50 years, the presence or absence of VaIN was not associated with any of the factors. However, the grade of VaIN lesions was significantly positively correlated with the grade of previous/concurrent cervical or vulvar lesions (Spearman Conclusion: The correlation between VaIN grade and prior lower genital tract lesions reverses with age, being negative in younger women and positive in older women. These findings underscore the necessity for age-stratified screening and management strategies for VaIN. In clinical practice, for women aged ≥50 years, greater emphasis should be placed on TCT screening results and the history of previous cervical/vulvar lesions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.