Evidence map›Paper›PMID 42369799›Full record

ArticleHeart rhythm O22026

The value of microelectrodes and microbipolar electrograms in premature ventricular complex mapping and ablation: The micro-PVC study.

Marco Bergonti, Nándor Szegedi, Paolo Compagnucci, Olivier Van Leuven, Tardu Özkartal, Maria Luce Caputo, Edit Tanai, Johan Saenen, Michela Casella, Giulio Conte

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Article in Heart rhythm O2, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

10 authors.

Marco BergontiCardiology department, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, Lugano, Switzerland.
Nándor SzegediCardiology Department, Heart and Vascular Center, Semmelweis University, Budapest, Hungary.
Paolo CompagnucciCardiology and Arrhythmology Clinic, University Hospital "Ospedali Riuniti", Ancona, Italy.
Olivier Van LeuvenCardiology Department, University Hospital Antwerp, Antwerp, Belgium.
Tardu ÖzkartalCardiology department, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, Lugano, Switzerland.
Maria Luce CaputoCardiology department, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, Lugano, Switzerland.
Edit TanaiCardiology Department, Heart and Vascular Center, Semmelweis University, Budapest, Hungary.
Johan SaenenCardiology Department, University Hospital Antwerp, Antwerp, Belgium.
Michela CasellaCardiology and Arrhythmology Clinic, University Hospital "Ospedali Riuniti", Ancona, Italy.
Giulio ConteFaculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Catheter ablation is an effective treatment for premature ventricular contractions (PVCs). Mapping typically relies on bipolar (bip-EGMs) and unipolar electrograms (uni-EGMs). Recently, catheters equipped with microbipolar electrodes have become available. Objective: This study aimed to investigate the value of microbipolar EGMs (micro-EGMs) in PVCs mapping. Methods: We performed a multicenter retrospective study including patients who underwent successful outflow tract PVC ablation using QDOT catheters. 2 groups were identified based on the superficial or intramural origin of the PVC. EGMs-bip-, uni-, and micro-EGMs-were assessed at the successful ablation sites. The primary outcome was the ability of micro-EGM to discriminate between superficial and intramural PVCs. The secondary outcome was signal amplitude. Results: Among 81 patients (mean age 54 ± 11 years; 59.3% male), 51 had superficial and 30 had intramural PVCs. In superficial PVC, micro-EGM preceded both uni-EGM and bip-EGM in 90% of cases. In particular, when the earliest bip-EGM preceded the earliest micro-EGM by >10 ms (Δ Conclusion: Micro-EGMs allow more accurate PVC mapping, improving depth estimation. Micro-EGMs seem to be valuable for local activation time annotation with important implications on automated annotation algorithms within existing electroanatomic mapping systems.

Indexed as

AblationMicrobipolarMicroelectrodesPremature ventricular contractionsQDOTVentricular

Identifiers

PMID42369799
PMCPMC13307482

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.