Evidence map›Paper›PMID 42369787›Full record

ArticleHeart rhythm O22026

Zero-contrast cardiac resynchronization therapy device implantation in heart failure patients with renal impairment.

Biagio Sassone, Marco Zuin, Angelo Melpignano, Martina De Raffele, Francesca Tiberia, Michele Malagù, Santo Virzì, Francesco Vitali, Cristina Balla, Enrico Bertagnin and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heart rhythm O2, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Biagio SassoneDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy.
Marco ZuinDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy.
Angelo MelpignanoCardiology Unit, Sant'Anna University Hospital, University of Ferrara, Ferrara, Italy.
Martina De RaffeleCardiology Unit, Sant'Anna University Hospital, University of Ferrara, Ferrara, Italy.
Francesca TiberiaCardiology Unit, Department of Cardio-Thoraco-Vascular Sciences, AUSL Ferrara, Cento, Ferrara, Italy.
Michele MalagùCardiology Unit, Sant'Anna University Hospital, University of Ferrara, Ferrara, Italy.
Santo VirzìCardiology Unit, Department of Cardio-Thoraco-Vascular Sciences, AUSL Ferrara, Cento, Ferrara, Italy.
Francesco VitaliCardiology Unit, Sant'Anna University Hospital, University of Ferrara, Ferrara, Italy.
Cristina BallaCardiology Unit, Sant'Anna University Hospital, University of Ferrara, Ferrara, Italy.
Enrico BertagninCardiology Unit, Department of Cardio-Thoraco-Vascular Sciences, AUSL Ferrara, Cento, Ferrara, Italy.
Matteo BertiniCardiology Unit, Sant'Anna University Hospital, University of Ferrara, Ferrara, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Coronary sinus venography is commonly used during cardiac resynchronization therapy (CRT) to guide left ventricular (LV) lead placement; however, iodinated contrast poses a substantial risk of contrast-induced acute kidney injury in patients with chronic kidney disease (CKD). Evidence supporting contrast-sparing CRT techniques remains limited. Objective: This study aimed to assess the feasibility, safety, and renal outcomes of a zero-contrast CRT implantation strategy in patients with CKD. Methods: Consecutive patients with CKD (estimated glomerular filtration rate [eGFR] <60 mL/min/1.73 m Results: Overall, 113 patients were analyzed. Zero-contrast implantation was successful in 57.5% of cases. Renal function remained stable after zero-contrast implantation (change in eGFR +3.6 mL/min/1.73 m Conclusion: Zero-contrast CRT implantation is feasible, safe, and effective, with better renal preservation in patients with CKD.

Indexed as

Cardiac resynchronization therapyChronic kidney diseaseContrast-induced nephropathyDeathHeart failure hospitalizationLeft ventricular lead

Identifiers

PMID42369787
PMCPMC13307477

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.