Evidence map›Paper›PMID 42369673›Full record

ArticleJournal of cardiovascular and thoracic research2026

Elevated asprosin levels in epicardial adipose tissue: Implications for coronary artery disease.

Hossein Shateri, Babak Manafi, Amir Hossein Yazdi, Sayed Mostafa Hosseini

Abstract read
In one paragraph

Article in Journal of cardiovascular and thoracic research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hossein ShateriStudent Research Committee, Baqiyatallah University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-2716-8941
Babak ManafiDepartment of Surgery, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.ORCID https://orcid.org/0000-0001-6834-3702
Amir Hossein YazdiClinical Research Development Unit Farshchian Heart Center, Department of Cardiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.ORCID https://orcid.org/0000-0003-1235-1433
Sayed Mostafa HosseiniChemical Injuries Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-3716-8133

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study investigates the role of the adipokine asprosin in coronary artery disease (CAD) by comparing its levels in epicardial adipose tissue (EAT) and serum between individuals with and without CAD. Asprosin is known to be involved in conditions such as insulin resistance and obesity, both of which are risk factors for CAD. Methods: The study included 25 CAD patients and 25 non-CAD patients undergoing open-heart surgery for valve issues. EAT samples were collected during surgery, and the mRNA levels of the FBN-1 gene were measured using qRT-PCR, while the protein levels of asprosin in both EAT and serum were determined using the ELISA method. Results: The results showed that the mRNA level of FBN-1 in the EAT of CAD patients was significantly higher than that in the control group ( Conclusion: These findings suggest that asprosin may play a critical role in the pathogenesis of CAD, particularly through its increased presence in EAT and serum. The study highlights the potential of asprosin as a biomarker for CAD, though further research is needed to fully understand its mechanisms in the progression of the disease.

Indexed as

AsprosinCoronary artery diseaseEpicardial adipose tissue

Identifiers

PMID42369673
PMCPMC13309332

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