Evidence map›Paper›PMID 42369618›Full record

ArticleACG case reports journal2026

The Role and Efficacy of Plasmapheresis in Acute Liver Failure Due to Hepatitis E Viral Hepatitis.

Sohail Hussain, Quratulain Khan, Fawad Hussain, Aimen Noor Ul Ain, Tauseef Mahmood, Faiza Nafees Khan

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sohail HussainDepartment of Gastroenterology, Ziauddin University, Karachi, Pakistan.
Quratulain KhanDepartment of Critical Care Medicine, Dr. Ziauddin University Hospital, Karachi, Pakistan.
Fawad HussainDepartment of Critical Care Medicine, Dr. Ziauddin University Hospital, Karachi, Pakistan.
Aimen Noor Ul AinDepartment of Gastroenterology, Ziauddin University, Karachi, Pakistan.ORCID https://orcid.org/0009-0008-9730-3863
Tauseef MahmoodDepartment of Gastroenterology, Ziauddin University, Karachi, Pakistan.
Faiza Nafees KhanDepartment of Gastroenterology, Ziauddin University, Karachi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute liver failure, due to hepatitis E virus (HEV) infection, represents a serious problem in developing countries, lacking access to liver transplantation. Therapeutic plasma exchange has become one potential bridge therapy, which has improved results by elimination of circulating toxins/inflammatory mediators, and ammonia. We describe the clinical course of a 31-year-old man who developed fulminant hepatic failure secondary to HEV infection. After conventional treatment, the patient underwent 5 sessions of plasmapheresis that was associated with marked biochemical and neurological recovery. This case provides support for plasmapheresis as a useful adjunct in the management of HEV-induced acute liver failure and its applicability in resource limited settings where liver transplantation is not available.

Indexed as

acute liver failure (ALF)hepatitis E virus (HEV)liver transplant alternativeplasmapheresistherapeutic plasma exchange (TPE)

Identifiers

PMID42369618
PMCPMC13308892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.