Evidence map›Paper›PMID 42369612›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2026

Novel Non-Valved Glaucoma Drainage Device with Reduced Inner Lumen Diameter: 6-Month Safety and Efficacy Outcomes.

Kelvin S Y Shi, Pranav Vasu, Kody Oyama, Ryan Y Thé, Melanie Wang, Raphael G Banoub, Bryan C H Ang, Syril K Dorairaj

Abstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kelvin S Y ShiDepartment of Ophthalmology, Mayo Clinic, Jacksonville, FL, USA.ORCID 0009-0004-0870-2901
Pranav VasuDepartment of Medicine, Creighton University School of Medicine, Phoenix, AZ, USA.
Kody OyamaDepartment of Medicine, Albert Einstein College of Medicine, New York, NY, USA.ORCID 0009-0007-6161-3010
Ryan Y ThéDepartment of Medicine, Wayne State University School of Medicine, Detroit, MI, USA.ORCID 0009-0006-5051-4570
Melanie WangDepartment of Medicine, Carle Illinois College of Medicine, Urbana, IL, USA.ORCID 0000-0002-5679-9259
Raphael G BanoubDepartment of Ophthalmology, Mayo Clinic, Jacksonville, FL, USA.
Bryan C H AngDepartment of Ophthalmology, Tan Tock Seng Hospital, Singapore, Singapore.
Syril K DorairajDepartment of Ophthalmology, Mayo Clinic, Jacksonville, FL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate the safety and clinical efficacy of the Ahmed ClearPath Methods: This retrospective chart review included 17 eyes that underwent ACP-ST implantation between February 25, 2025, and November 24, 2025. Surgical success was defined as a ≥20% reduction in IOP from baseline with a postoperative IOP >5 mmHg and no need for additional surgical intervention. Changes in IOP, glaucoma medication burden, and best-corrected visual acuity (BCVA) were evaluated through 6 months. Intraoperative and postoperative complications were recorded. Results: Fourteen eyes had available 6-month follow-up data. Mean IOP decreased from 27.19 ± 6.29 mmHg at baseline to 12.21 ± 5.45 mmHg at 6 months, representing a 55.1% reduction (P < 0.0001). Mean glaucoma medication use decreased from 3.35 ± 1.14 to 1.07 ± 0.99 medications, corresponding to a 68.1% reduction (P < 0.0001). Surgical success was achieved in all 14 eyes (100%) with available 6-month follow-up. No intraoperative complications occurred, and no cases of postoperative hypotony or IOP spikes were observed. Conclusion: These preliminary findings suggest that ACP-ST may achieve clinically meaningful reductions in IOP and glaucoma medication burden while maintaining a favorable short-term safety profile, as no cases of postoperative hypotony or IOP spikes were observed. However, given the retrospective design, small sample size, and limited duration of follow-up, further longitudinal studies with larger cohorts will be necessary to better evaluate the durability and long-term safety of ACP-ST.

Indexed as

Ahmed ClearPath Small-TubeAhmed implantsGlaucomaglaucoma drainage device

Identifiers

PMID42369612
PMCPMC13310067

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.