Evidence map›Paper›PMID 42369419›Full record

ArticleNAM journal2025

Pursuing societal impact in research projects on NAM development: An analysis of routes to impact.

Tessel B Wijne, Wouter P C Boon, Anne S Kienhuis, Ellen H M Moors, Jarno Hoekman

Abstract read
In one paragraph

Article in NAM journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tessel B WijneCopernicus Institute of Sustainable Development, Utrecht University, Utrecht, The Netherlands.
Wouter P C BoonCopernicus Institute of Sustainable Development, Utrecht University, Utrecht, The Netherlands.
Anne S KienhuisNational Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
Ellen H M MoorsCopernicus Institute of Sustainable Development, Utrecht University, Utrecht, The Netherlands.
Jarno HoekmanCopernicus Institute of Sustainable Development, Utrecht University, Utrecht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New Approach Methodologies (NAMs) for risk assessment of chemicals and pharmaceuticals are widely regarded as essential for phasing out animal testing and advancing next-generation risk assessment. However, despite substantial public investments in research and development (R&D) to develop these NAMs, concerns persist about the limited societal impact of these projects. This study addresses this concern by examining how societal impact is pursued in sixteen large-scale, publicly-funded European R&D projects focused on developing NAMs that integrate

Indexed as

Animal-free Risk AssessmentNew Approach MethodologiesRoutes to ImpactSocietal ImpactStakeholder Engagement

Identifiers

PMID42369419
PMCPMC13288644

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.