ArticleFrontiers in neurology
Timing of nasogastric tube placement after endovascular thrombectomy and risk of stroke-associated pneumonia: a retrospective cohort study.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Stroke-associated pneumonia (SAP) is a common complication following endovascular thrombectomy (EVT), yet the impact of nasogastric tube (NGT) placement timing on SAP risk has not been examined. Methods: We conducted a single-center retrospective cohort study of 331 patients who underwent successful EVT and received NGT placement between June 2022 and May 2025. The primary exposure was time from reperfusion to NGT placement. Multivariable logistic regression and restricted cubic splines were used to examine the association between NGT timing and SAP, adjusting for age, sex, admission NIHSS score, serum albumin, hypertension, atrial fibrillation, and diabetes mellitus. Results: Stroke-associated pneumonia occurred in 227 patients (68.6%), reflecting the cohort's restriction to EVT patients requiring NGT placement, a high-aspiration-risk subgroup. Each 12-h delay in NGT placement was associated with a 33% increase in the adjusted odds of SAP (aOR 1.33, 95% CI 1.06-1.68, Conclusion: In EVT-treated patients requiring NGT placement, longer time to NGT insertion was associated with higher SAP risk after adjustment for measured covariates. These findings suggest that NGT placement timing may be a potentially modifiable factor in post-EVT care, and provide a hypothesis-generating basis for prospective evaluation.
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