Evidence map›Paper›PMID 42369193›Full record

ArticleJournal of statistical software2025

ebnm: An R Package for Solving the Empirical Bayes Normal Means Problem Using a Variety of Prior Families.

Jason Willwerscheid, Peter Carbonetto, Matthew Stephens

Abstract read
In one paragraph

Article in Journal of statistical software, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. A Gene-Program Architecture of Mouse T cells.bioRxiv : the preprint server for biology · 2026
    Article
  3. Empirical Bayes Covariance Decomposition, and a Solution to the Multiple Tuning Problem in Sparse PCA.Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Covariate-moderated Empirical Bayes Matrix Factorization.Advances in neural information processing systems · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jason WillwerscheidProvidence College.ORCID 0000-0002-7423-418X
Peter CarbonettoUniversity of Chicago.ORCID 0000-0003-1144-6780
Matthew StephensUniversity of Chicago.ORCID 0000-0001-5397-9257

Funding

Genome analysis: statistical methods and applicationsR01HG002585 · NHGRI · UNIVERSITY OF WASHINGTON · PI MATTHEW STEPHENS · 2002 to 2026
$8.4M
NHGRI NIH HHS R01 HG002585
6 · The paper itself

Abstract

The empirical Bayes normal means (EBNM) model is important to many areas of statistics, including (but not limited to) multiple testing, wavelet denoising, and gene expression analysis. There are several existing software packages that can fit EBNM models under different prior assumptions and using different algorithms. However, the differences across interfaces complicate direct comparisons, and a number of important prior assumptions do not yet have implementations. Motivated by these issues, we developed the R package

Indexed as

empirical Bayesmaximum likelihoodmixture modelsnormal meansNPMLEshrinkage estimation

Identifiers

PMID42369193
PMCPMC13308579

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.