Evidence map›Paper›PMID 42369164›Full record

ArticleFrontiers in medicine2026

The predictive value of

Ruihe Lai, Dandan Sheng, Yuzhi Geng, Chongyang Ding, Qianqian Tan, Lianjun Zhao

Abstract read
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ruihe LaiDepartment of Nuclear Medicine, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, China.
Dandan ShengDepartment of Nuclear Medicine, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yuzhi GengDepartment of Nuclear Medicine, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Chongyang DingDepartment of Nuclear Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Qianqian TanDepartment of Nuclear Medicine, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, China.
Lianjun ZhaoThe Comprehensive Cancer Center of Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study assessed the utility of baseline Methods: A total of 724 patients from two centers were allocated to training, validation, and test cohorts. Peritumoral regions were delineated with 2-8 mm radial expansions using LIFEx, while tumor habitat subregions were identified via k-means clustering. Multiple machine learning algorithms were employed to develop clinical-metabolic, intratumoral, peritumoral, habitat, and combined models. Model performance was assessed using AUC, calibration curves, DCA, and DeLong tests, and SHAP analysis was applied to interpret critical predictive features. Results: In the test cohort, the combined model achieved the highest and most favorable predictive performance for EGFR mutation (AUC = 0.862, 95% CI: 0.80-0.93), followed by the habitat model (AUC = 0.831, 95% CI: 0.76-0.90). Both models significantly outperformed all other models across datasets (all Conclusion: Baseline

Indexed as

18F-FDG PET/CTEGFR mutationslung adenocarcinomaperitumoral radiomicsSHAP analysistumor habitat

Identifiers

PMID42369164
PMCPMC13303213

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.