SynthesisFrontiers in medicine2026
Effects of mind-body training on upper-limb function in stroke patients: a multilevel dose-response meta-analysis.
Synthesis in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This systematic review and meta-analysis examined the effects of mind-body training (MBT) on upper-limb function in patients with stroke. A Bayesian dose-response model and an XGBoost-SHAP analysis were used to assess the optimal intervention dosage and to determine key factors influencing outcomes. Methods: PubMed, Web of Science, PsycINFO, and the Cochrane Library were searched from their inception to January 10, 2026, for randomized controlled trials. Effect sizes were calculated as standardized mean differences (SMDs). Risk of bias was assessed using ROB2. Analyses included Egger's test, trim-and-fill, sensitivity analysis, subgroup analysis, meta-regression, trial sequential analysis, and Bayesian hierarchical dose-response modeling. XGBoost-SHAP was used for exploratory analysis of predictors. Results: Conclusion: Moderate-certainty evidence indicates that MBT effectively enhances upper-limb function in stroke patients, with the best results seen at around 33.5 total h. A schedule of 30-min sessions, five times a week for 14-15 weeks, may provide preliminary guidance for future dose-stratified trials and clinical planning, particularly in studies involving subacute-stage patients, although this finding should be confirmed in future stage-stratified RCTs. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420261334249, identifier: CRD420261334249.
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