Evidence map›Paper›PMID 42369021›Full record

ArticleRegenerative biomaterials2026

Holmium vanadate nanoparticles as a biosafe and efficient contrast agent for spectral CT imaging of gastritis and colitis.

Wenqian Ru, Chunmei Yang, Xin Zhu, Yanlin Wu, Fei Pei, Haoran Chen, Yuanyuan Ma, Qiuyu Meng, Lu Yang, Yong Xu

Abstract read

In one paragraph

Article in Regenerative biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Wenqian RuDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Southwest Medical University, Sichuan Clinical Research Center for Nephropathy, Metabolic Vascular Disease Key Laboratory of Sichuan Province, and Sichuan-Chongqing Joint Key Laboratory of Metabolic Vascular Diseases, Luzhou, Sichuan 646000, China.

Chunmei YangDepartment of Radiology, The Affiliated Hospital, Southwest Medical University, Precision Imaging and Intelligent Analysis Key Laboratory of Luzhou, Luzhou, Sichuan 646000, China.

Xin ZhuDepartment of Radiology, The Affiliated Hospital, Southwest Medical University, Precision Imaging and Intelligent Analysis Key Laboratory of Luzhou, Luzhou, Sichuan 646000, China.

Yanlin WuDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Southwest Medical University, Sichuan Clinical Research Center for Nephropathy, Metabolic Vascular Disease Key Laboratory of Sichuan Province, and Sichuan-Chongqing Joint Key Laboratory of Metabolic Vascular Diseases, Luzhou, Sichuan 646000, China.

Fei PeiDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Southwest Medical University, Sichuan Clinical Research Center for Nephropathy, Metabolic Vascular Disease Key Laboratory of Sichuan Province, and Sichuan-Chongqing Joint Key Laboratory of Metabolic Vascular Diseases, Luzhou, Sichuan 646000, China.

Haoran ChenDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Southwest Medical University, Sichuan Clinical Research Center for Nephropathy, Metabolic Vascular Disease Key Laboratory of Sichuan Province, and Sichuan-Chongqing Joint Key Laboratory of Metabolic Vascular Diseases, Luzhou, Sichuan 646000, China.

Yuanyuan MaDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Southwest Medical University, Sichuan Clinical Research Center for Nephropathy, Metabolic Vascular Disease Key Laboratory of Sichuan Province, and Sichuan-Chongqing Joint Key Laboratory of Metabolic Vascular Diseases, Luzhou, Sichuan 646000, China.

Qiuyu MengZhejiang Collaborative Innovation Center for Full-Process Monitoring and Green Governance of Emerging Contaminants, Interdisciplinary Research Academy (IRA), Zhejiang Shuren University, Hangzhou 310015, China.

Lu YangDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Southwest Medical University, Sichuan Clinical Research Center for Nephropathy, Metabolic Vascular Disease Key Laboratory of Sichuan Province, and Sichuan-Chongqing Joint Key Laboratory of Metabolic Vascular Diseases, Luzhou, Sichuan 646000, China.

Yong XuDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Southwest Medical University, Sichuan Clinical Research Center for Nephropathy, Metabolic Vascular Disease Key Laboratory of Sichuan Province, and Sichuan-Chongqing Joint Key Laboratory of Metabolic Vascular Diseases, Luzhou, Sichuan 646000, China.ORCID https://orcid.org/0000-0002-9534-6252

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of a biosafe and high-performance spectral computed tomography (CT) contrast agent for the specific and non-invasive diagnosis of gastrointestinal diseases represents a significant clinical need. Unlike conventional CT, which is susceptible to artifacts from polychromatic X-ray beams, spectral CT distinguishes itself by utilizing material-specific, energy-dependent attenuation data. This capability enables superior differentiation between tissue types, leading to reduced background noise and improved contrast specificity. In this study, we developed hyaluronic acid-functionalized holmium vanadate nanoparticles (HA-HoVO

Indexed as

clinical translationcolitisCT contrast agentgastritisspectral CT imaging

Identifiers

PMID42369021

DOI10.1093/rb/rbag106

PMCPMC13294444

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.