ArticlePhysical review applied2025
Changes in bubble-cloud dissolution throughout the application of histotripsy pulses.
Article in Physical review applied, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Material damage is a consideration for any applications where pressure fields may initiate cavitation. Histotripsy is a focused ultrasound therapy that exploits the destructive property of bubble clouds to disrupt viscoelastic tissue. The resulting effect achieves the same outcomes as surgery without the need for an invasive procedure. This study investigated the relationship between changes in bubble clouds throughout focused ultrasound exposure. Specifically, the dissolution period of bubbles generated in water and agarose gel was tracked with ultrafast ultrasound imaging. This imaging marker was found to increase in agarose during the initial stages of exposure, and maintained steady-state values after 555 ± 64 applied histotripsy pulses. The relative change in damage area of the gel and bubble-dissolution period with exposure duration were found to be equivalent (
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Registered trials
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