Evidence map›Paper›PMID 42368820›Full record

SynthesisFrontiers in psychiatry2026

Telerehabilitation in children and adolescents with intellectual disability: a systematic review.

Martina Micai, Letizia Gila, Angela Caruso, Daniela Morelli, Maria Grazia Totino, Giulia Balboni, Carmen Belacchi, Alessandra Colucci, Chiara Fantini, Tiziana Metitieri and 7 more

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Martina MicaiNational Center for Rare Diseases, Istituto Superiore di Sanità, Rome, Italy.
Letizia GilaNational Center for Rare Diseases, Istituto Superiore di Sanità, Rome, Italy.
Angela CarusoNational Center for Rare Diseases, Istituto Superiore di Sanità, Rome, Italy.
Daniela MorelliFondazione Santa Lucia IRCCS, Rome, Italy.
Maria Grazia TotinoCentro Ricerca e Cura (CRC) Research and Care Center of Rome, Rome, Italy.
Giulia BalboniUniversity of Bologna, Bologna, Italy.
Carmen BelacchiUniversity of Urbino Carlo Bo, Urbino, Italy.
Alessandra ColucciAzienda Sanitaria Locale (ASL) Bari, Bari, Italy.
Chiara FantiniFondazione Santa Lucia IRCCS, Rome, Italy.
Tiziana MetitieriAzienda Ospedaliero-Universitaria (AOU) Meyer IRCCS, Firenze, Italy.
Margherita OrsoliniDepartment of Developmental and Socialization Psychology, Sapienza University of Rome, Rome, Italy.
Alessandra RampazziFondazione Santa Lucia IRCCS, Rome, Italy.
Ciro RuggeriniProgetto Crescere Social Cooperative, Reggio Emilia, Italy.
Cristiana StefaniFondazione Santa Lucia IRCCS, Rome, Italy.
Marco BertelliCREA - Research and Clinical Center - San Sebastiano Foundation, Misericordia di Firenze, Florence, Italy.
Francesca FulceriNational Center for Rare Diseases, Istituto Superiore di Sanità, Rome, Italy.
Maria Luisa ScattoniNational Center for Rare Diseases, Istituto Superiore di Sanità, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: In recent years, telerehabilitation has been increasingly used to improve access to care for children and adolescents with intellectual disability (ID). However, the available evidence is still limited and highly heterogeneous. This systematic review aimed to evaluate the impact of telerehabilitation interventions on cognitive, behavioural, and functional outcomes in this population. Materials and methods: This systematic review was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and registered in International Prospective Register of Systematic Reviews (PROSPERO) (CRD420251005874). A comprehensive search of PubMed and Web of Science databases was performed from inception to March 12, 2026. Eligible studies included randomized controlled trials and observational studies investigating telerehabilitation interventions in children and adolescents (≤18 years) with ID. Results: A total of 28 studies involving 668 participants were included. Interventions encompassed a wide range of approaches, including parent-mediated programmes, cognitive training, behavioural interventions, and tele-coaching models. Across studies, telerehabilitation was generally associated with improvements in language and communication skills, challenging behaviours, executive functions, and motor outcomes. Parent-mediated and telehealth-delivered behavioural interventions showed evidence, especially in reducing externalizing behaviours and parental stress. Digital cognitive training programmes showed feasibility and short-term gains in working memory and attention, although long-term effects were less consistent. Interventions targeting lifestyle and mental health showed promising but preliminary results. However, studies differed substantially in design, intervention protocols, and outcome measures, along with frequent methodological limitations. Discussion: Telerehabilitation appears to be a feasible and potentially effective approach for supporting children and adolescents with ID, particularly when caregivers are actively involved. Larger and methodologically robust studies are needed to better define intervention characteristics and assess long-term outcomes, as well as on the development of hybrid care models integrating in-person and remote approaches. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/, identifier CRD420251005874.

Indexed as

caregiver-mediated interventiondigital health interventionsintellectual and developmental disabilitiesonline therapyremote interventionservice delivery modelstelehealthtelemedicine

Identifiers

PMID42368820
PMCPMC13294227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.