ArticleHealth science reports2026
The Effect of Ostrich Oil on Pain, Healing, and Recurrence of Chronic Anal Fissure: A Randomized Controlled Double-Blind Clinical Trial.
Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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9 authors.
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Abstract
Background and Aims: An anal fissure is a tear in the anal canal below the dentate line, affecting one in five people at some point in their lives. Researchers continuously seek new medications for treating this condition. Ostrich oil has shown anti-inflammatory and analgesic effects on wounds, as well as angiogenic and re-epithelialization properties. This study aims to evaluate the effect of ostrich oil on pain reduction and healing in patients with chronic anal fissure (CAF), with implications for improving home-based palliative care strategies. Method: In this clinical trial, 150 patients with CAF were randomly divided into intervention and glyceryl trinitrate (GTN) therapy groups. The intervention group received a combination of GTN 0.2% and ostrich oil 50%, while the GTN therapy group received 0.2% GTN ointment until recovery. Patients were evaluated for visual analog scale (VAS), bleeding, healing, and recurrence with a checklist. Results: Results showed that ostrich oil significantly reduced pain scores compared to GTN over time (group × time interaction: Conclusion: The results of this study suggest that ostrich oil may reduce pain, accelerate healing, shorten the treatment duration, and prevent recurrence of CAF. Given its ease of application and favorable safety profile, ostrich oil could be considered a valuable component of home-based palliative care strategies for managing CAF.
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