Evidence map›Paper›PMID 42368592›Full record

ArticleEULAR rheumatology open2025

Patient self-assessment and virtual visit-based treatment decisions in rheumatoid arthritis: results from the multicentre Telemedicine in Rheumatoid Arthritis trial.

Johannes Knitza, Johanna Mucke, Felix Muehlensiepen, Tingting Xiong, Manuel Grahammer, Julia Greenfield, Sebastian Kuhn, Nicolas Vuillerme, Gerhard Krönke, Georg Schett and 2 more

Abstract read
In one paragraph

Article in EULAR rheumatology open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Johannes KnitzaInstitute for Digital Medicine, School of Medicine, Philipps-Universität Marburg, Marburg, Germany.
Johanna MuckeRheumazentrum Ruhrgebiet, Ruhr-Universität Bochum, Herne, Germany.
Felix MuehlensiepenCenter for Health Services Research, Brandenburg Medical School Theodor Fontane, Rüdersdorf, Germany.
Tingting XiongDivision of Rheumatology and Systemic Inflammatory Diseases, III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Manuel GrahammerCenter for Health Services Research, Brandenburg Medical School Theodor Fontane, Rüdersdorf, Germany.
Julia GreenfieldInstitute for Digital Medicine, School of Medicine, Philipps-Universität Marburg, Marburg, Germany.
Sebastian KuhnInstitute for Digital Medicine, School of Medicine, Philipps-Universität Marburg, Marburg, Germany.
Nicolas VuillermeAGEIS, Université Grenoble Alpes, Grenoble, France.
Gerhard KrönkeDepartment of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Georg SchettDepartment of Internal Medicine, Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.
Ann-Christin PecherDepartment of Internal Medicine II, Hematology, Oncology, Clinical Immunology, and Rheumatology, University Hospital Tübingen, Tübingen, Germany.
Martin KruscheDivision of Rheumatology and Systemic Inflammatory Diseases, III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The growing shortage of rheumatologists threatens rheumatology care. Patient self-assessment and asynchronous virtual visits may improve efficiency. This study assessed the concordance of face-to-face (F2F) and virtual visit-based treatment decisions in individuals with rheumatoid arthritis (RA), incorporating patient self-assessment. Methods: This prospective 3-month multicentre trial recruited RA patients across 4 university centres in Germany. Patients used a medical app to document the results of a self-performed C-reactive protein (CRP) test, joint count, therapeutic suggestions, and electronic patient-reported outcomes (ePROs) before their regular F2F consultations and ePROs on a weekly basis in-between consultations. Independent tele-rheumatologists provided treatment recommendations based on these data. The primary outcome was the level of agreement between tele-rheumatologists and patients on treatment decisions (escalation, unchanged, de-escalation), compared with F2F rheumatologists' decisions. Secondary outcomes included change in patient activation (Patient Activation Measure [PAM]) and in patient-perceived ability to assess their disease activity. Results: A total of 208 consultations and 114 patients (80.7% female, mean age 51.6 years) were included. Most often (63%), treatment remained unchanged, whereas 24% required escalation and 14% de-escalation. F2F treatment decisions aligned with tele-rheumatologist decisions in 77% of cases and patient suggestions in 67% of cases. The accuracy of tele-rheumatologist decisions was 77% for maintaining treatment, 87% for de-escalation, and 91% for escalation. No significant changes in patient activation and patients' ability to assess their disease activity were observed. Conclusions: The study demonstrated substantial agreement between virtual asynchronous and F2F treatment decisions. However, further refinement of asynchronous care models and validation studies is crucial.

Identifiers

PMID42368592
PMCPMC13292483

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.