Evidence map›Paper›PMID 42368537›Full record

ArticleFrontiers in plant science2026

Integrated analysis of metabolome and transcriptome reveals the mechanism of divergent acute heat stress responses in mango cultivars.

Wenju Luo, Xianbin Hou, Lanjie Wei, Shiheng Liu, Ruixia Li, Zheng Teng, Cuifeng Yang, Yufeng Li, Zhengjie Zhu

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In one paragraph

Article in Frontiers in plant science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Wenju Luo *Guangxi Key Laboratory of Biology for Mango, College of Agriculture and Food Engineering, Baise University, Baise, China.
Xianbin Hou *Guangxi Key Laboratory of Biology for Mango, College of Agriculture and Food Engineering, Baise University, Baise, China.
Lanjie WeiGuangxi Key Laboratory of Biology for Mango, College of Agriculture and Food Engineering, Baise University, Baise, China.
Shiheng LiuGuangxi Key Laboratory of Biology for Mango, College of Agriculture and Food Engineering, Baise University, Baise, China.
Ruixia LiGuangxi Key Laboratory of Biology for Mango, College of Agriculture and Food Engineering, Baise University, Baise, China.
Zheng TengGuangxi Key Laboratory of Biology for Mango, College of Agriculture and Food Engineering, Baise University, Baise, China.
Cuifeng YangGuangxi Key Laboratory of Biology for Mango, College of Agriculture and Food Engineering, Baise University, Baise, China.
Yufeng LiGuangxi Key Laboratory of Biology for Mango, College of Agriculture and Food Engineering, Baise University, Baise, China.
Zhengjie ZhuGuangxi Key Laboratory of Biology for Mango, College of Agriculture and Food Engineering, Baise University, Baise, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Mango ( Results and discussion: Heat stress induces multiple physiological impairments in mango seedlings through oxidative stress. Metabolome analysis identified 12 major metabolite classes, with amino acids and derivatives (AADs), phenolic acids (PAs), flavonoids (FLs), and lignans and coumarins (Lc) being the most responsive to acute heat stress, which provides a solid basis for subsequent research. RNA-seq analysis revealed that 12,635 differentially expressed genes (DEGs) were related to photosynthesis, homeostasis regulation, stomatal regulation, and other key plant hormone pathways. Weighted gene co-expression network analysis identified that copper chaperone, cytochrome c, and 5'-AMP-activated protein kinase (AMPK) were the key genes involved in acute heat stress response. Integrated Pearson correlation analysis across 36 samples revealed a strong, statistically significant gene-metabolite network (|r| > 0.7, p < 0.001), with AMPK showing the most extensive associations to lipids, flavonoids, and amino acid derivatives. These findings provide a unique theoretical basis for studying early heat-stress response mechanisms and for genetic breeding of mango, and offer valuable information for breeding heat-tolerant mango varieties.

Indexed as

5’-AMP-activated protein kinase (AMPK)copper chaperonecytochrome cheat stressMangifera indica L.

Identifiers

PMID42368537
PMCPMC13303361

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