Evidence map›Paper›PMID 42368483›Full record

ArticleCase reports in infectious diseases2026

A Case Series Demonstrating the Spectrum of Invasive Methicillin-Sensitive

Elisée Mbombo, Mubarack Ayamie, James Makina, Doreen Phiri, Natasha Banda, Zainab Maluk, McPherson Mahala, Humphry Chisambiro, Nohakhelha Nyamulani, Franck Phoya and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Elisée MbomboPathology Department, Kamuzu University of Health Sciences, Southern Region, Blantyre, Malawi.ORCID https://orcid.org/0000-0003-2669-1279
Mubarack AyamiePediatrics and Child Health Department, Queen Elizabeth Central Hospital, Southern Region, Blantyre, Malawi.
James MakinaPediatrics and Child Health Department, Queen Elizabeth Central Hospital, Southern Region, Blantyre, Malawi.
Doreen PhiriPediatrics and Child Health Department, Queen Elizabeth Central Hospital, Southern Region, Blantyre, Malawi.
Natasha BandaPediatrics and Child Health Department, Queen Elizabeth Central Hospital, Southern Region, Blantyre, Malawi.
Zainab MalukPediatrics and Child Health Department, Queen Elizabeth Central Hospital, Southern Region, Blantyre, Malawi.
McPherson MahalaTrauma and Orthopedics, Surgery Department, Queen Elizabeth Central Hospital, Southern Region, Blantyre, Malawi.
Humphry ChisambiroEmergency Medicine Department, Queen Elizabeth Central Hospital, Southern Region, Blantyre, Malawi.
Nohakhelha NyamulaniTrauma and Orthopedics, Surgery Department, Queen Elizabeth Central Hospital, Southern Region, Blantyre, Malawi.
Franck PhoyaPediatrics and Child Health Department, Queen Elizabeth Central Hospital, Southern Region, Blantyre, Malawi.
George ChagalukaPediatrics and Child Health Department, Queen Elizabeth Central Hospital, Southern Region, Blantyre, Malawi.
Patrick MapembaTrauma and Orthopedics, Surgery Department, Queen Elizabeth Central Hospital, Southern Region, Blantyre, Malawi.
Emmie MbalePediatrics and Child Health Department, Queen Elizabeth Central Hospital, Southern Region, Blantyre, Malawi.
David KulapaniPathology Department, Kamuzu University of Health Sciences, Southern Region, Blantyre, Malawi.
Alix N KaminaSchool of Public Health, Université Officielle de Mbujimayi, Kasaï Oriental, Mbujimayi, Democratic Republic of the Congo.
Criss K MjumbeSchool of Public Health, Université de Lubumbashi, Haut Katanga, Lubumbashi, Democratic Republic of the Congo.ORCID https://orcid.org/0000-0002-6088-2629
Josephine LangtonPediatrics and Child Health Department, Queen Elizabeth Central Hospital, Southern Region, Blantyre, Malawi.
Yamikani ChimalizeniPediatrics and Child Health Department, Queen Elizabeth Central Hospital, Southern Region, Blantyre, Malawi.
Kondwani KawazaPediatrics and Child Health Department, Queen Elizabeth Central Hospital, Southern Region, Blantyre, Malawi.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Case Report: We present 4 cases of previously healthy children who presented with various clinical manifestations, but skin lesions and fever were common in all of them. They had multisystem involvement and eventually required aggressive multifactorial therapy. Antibiotic treatment was tailored to the results of antimicrobial sensitivity tests following blood culture. Though the hospital stay was quite long, intensive care and appropriate antibiotics contributed to a good prognosis. Conclusion: In children with invasive MSSA disease, early diagnosis and prompt management are key factors to improved prognosis. Skin lesions with tender joints in a febrile infant should raise suspicion for a staphylococcal infection. Intensive care and infection source control are the cornerstones of the management.

Indexed as

disseminated staphylococcal infectioninvasive MSSA diseaseseptic arthritisskin lesionsStaphylococcus aureus

Identifiers

PMID42368483
PMCPMC13296220

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.