Evidence map›Paper›PMID 42368120›Full record

ArticleACS omega2026

Lacrimal Drainage Catheter Coated with Mitomycin C to Inhibit Fibrosis after Canalicular Laceration Repair.

Huanhuan Xu, Liang Lu, Xueying Kong, Rui Wu, Hu Meng, Dekui Ren, Jun Gu, Yong Wu, Yirui Ge

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Huanhuan XuDepartment of Ophthalmology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210093, China.
Liang LuState Key Laboratory of Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications, Nanjing 210003, China.ORCID https://orcid.org/0009-0002-7841-8987
Xueying KongResearch Institute of General Surgery, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210093, China.
Rui WuDepartment of pharmacy, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210093, China.
Hu MengDepartment of Ophthalmology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210093, China.
Dekui RenDepartment of Ophthalmology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210093, China.
Jun GuResearch Institute of General Surgery, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210093, China.
Yong WuDepartment of Ophthalmology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210093, China.
Yirui GeDepartment of Ophthalmology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210093, China.ORCID https://orcid.org/0009-0009-4653-1142

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canalicular lacerations represent a common ocular emergency that can lead to significant complications if not managed promptly and effectively. Silicone stents are the most commonly chosen option due to their favorable characteristics. However, postoperative complications, such as canalicular stenosis, remain prevalent, necessitating the exploration of additional therapeutic strategies. Mitomycin C (MMC) is an effective agent for preventing excessive fibrosis in various ophthalmic surgeries; however, its topical application faces challenges due to rapid clearance and potential side effects. Currently, we have established a dual-layer drug delivery system for MMC, wherein lacrimal drainage catheters (LDC) were coated with agarose loaded with MMC (MA-1, MA-2, and MA-3) and subsequently encapsulated in a layer of poly-(lactic-

Identifiers

PMID42368120
PMCPMC13295034

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.