Evidence map›Paper›PMID 42368104›Full record

ArticleACS omega2026

Glycine-Copper Nanozyme with Dual Oxidase Activity: for Colorimetric Detection of Epinephrine and Oxidation of Phenolic Pollutants.

Bitania Teklu Yilma, Menbere Leul Mekonnen, Kaayyoof Fikadu Gutema, Tesfaye Eshete Asrat, Jan Dellith, Marco Diegel, Andrea Csáki, Wolfgang Fritzsche

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In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bitania Teklu YilmaIndustrial Chemistry Department, Addis Ababa Science and Technology University, Addis Ababa P.O. Box 1647, Ethiopia.
Menbere Leul MekonnenIndustrial Chemistry Department, Addis Ababa Science and Technology University, Addis Ababa P.O. Box 1647, Ethiopia.ORCID https://orcid.org/0000-0001-9617-853X
Kaayyoof Fikadu GutemaIndustrial Chemistry Department, Addis Ababa Science and Technology University, Addis Ababa P.O. Box 1647, Ethiopia.
Tesfaye Eshete AsratIndustrial Chemistry Department, Addis Ababa Science and Technology University, Addis Ababa P.O. Box 1647, Ethiopia.ORCID https://orcid.org/0000-0001-9885-3404
Jan DellithCompetence Center for Micro- and Nanotechnologies, Microstructure Analysis Group, Leibniz Institute of Photonic Technology (Leibniz-IPHT), Albert-Einstein-Strasse 9, Jena 07745, Germany.
Marco DiegelCompetence Center for Micro- and Nanotechnologies, Microstructure Analysis Group, Leibniz Institute of Photonic Technology (Leibniz-IPHT), Albert-Einstein-Strasse 9, Jena 07745, Germany.
Andrea CsákiNanobiophotonics Department, Leibniz Institute of Photonic Technology (Leibniz-IPHT), Albert-Einstein-Strasse 9, Jena 07745, Germany.
Wolfgang FritzscheNanobiophotonics Department, Leibniz Institute of Photonic Technology (Leibniz-IPHT), Albert-Einstein-Strasse 9, Jena 07745, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Developing nanozymes with well-defined yet synthetically simple coordination environments remains essential from a rational design perspective. Here, we present a minimalistic glycine-copper (GCu) nanozyme, where the smallest amino acid acts as the only ligand to stabilize mixed-valence Cu-(I)/Cu-(II) centers. Structural analysis confirms the formation of a glycine-coordinated copper complex in a distinct mixed-valence state, supporting efficient phenol oxidase-like catalysis. The GCu nanozyme shows catechol oxidase activity toward epinephrine (EP), catalyzing its oxidation to adrenochrome, which strongly absorbs at 486 nm. Kinetic studies across different buffer systems reveal that GCu exhibits the highest catalytic turnover (K

Identifiers

PMID42368104
PMCPMC13295036

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.