Evidence map›Paper›PMID 42367950›Full record

ArticlebioRxiv : the preprint server for biology2026

Exposure to perfluorooctanoic acid accelerates

Eric A Kilbourn, Matthew R Lowe, Kanishka Panda, Akshay M Bhaskaran, Guomao Zheng, Aditi R Aalati, Adam Malave, Sophia White, Anna Graber, Nika Zulkowski and 8 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Eric A KilbournDepartment of Biology, Indiana University, Bloomington, Indiana 47405, USA.
Matthew R LoweDepartment of Biology, Indiana University, Bloomington, Indiana 47405, USA.
Kanishka PandaDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.
Akshay M BhaskaranDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.
Guomao ZhengPaul H. O'Neill School of Public and Environmental Affairs, Indiana University, Bloomington, Indiana 47405 Unites States.
Aditi R AalatiDepartment of Biology, Indiana University, Bloomington, Indiana 47405, USA.
Adam MalaveDepartment of Biology, Indiana University, Bloomington, Indiana 47405, USA.
Sophia WhiteDepartment of Biology, Indiana University, Bloomington, Indiana 47405, USA.
Anna GraberDepartment of Biology, Indiana University, Bloomington, Indiana 47405, USA.
Nika ZulkowskiDepartment of Biology, Indiana University, Bloomington, Indiana 47405, USA.
Robert PepinDepartment of Chemistry, Indiana University, Bloomington, IN, 47405, USA.
Amina SalamovaGangarosa Department of Environmental Health, Emory, Atlanta, Georgia 30322, USA.
Travis NemkovDepartment of Biochemistry and Molecular Genetics, Anschutz Medical Campus, University of Colorado School of Medicine, Aurora, CO, 80045, USA.ORCID 0000-0001-8566-7119
Angelo D'AlessandroDepartment of Biochemistry and Molecular Genetics, Anschutz Medical Campus, University of Colorado School of Medicine, Aurora, CO, 80045, USA.ORCID 0000-0002-2258-6490
Swathi YadlapalliDepartment of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA.
Pramod ReddyDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.
Edgar MeyhoferDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.
Jason M TennessenDepartment of Biology, Indiana University, Bloomington, Indiana 47405, USA.ORCID 0000-0002-3527-5683

Funding

Resource Project CoreU41HG000739 · NHGRI · HARVARD UNIVERSITY · PI PERRIMON, NORBERT · 2014 to 2022
$32.3M
Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
A Drosophila Model for the Regulation of Aerobic GlycolysisR35GM119557 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI Jason Michael Tennessen · 2016 to 2026
$4.7M
Spatiotemporal mechanisms controlling circadian rhythmsR35GM133737 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Swathi Yadlapalli · 2019 to 2026
$3.4M
Investigating metabolic responses to high sugar diets and the onset of diabetic phenotypesR01DK136945 · NIDDK · TRUSTEES OF INDIANA UNIVERSITY · PI Angelo D'Alessandro, NORBERT PERRIMON · 2023 to 2026
$2.4M
NCATS NIH HHS UL1 TR002529NHGRI NIH HHS U41 HG000739NIDDK NIH HHS R01 DK136945NIGMS NIH HHS R35 GM119557NIGMS NIH HHS R35 GM133737NIH HHS P40 OD018537
6 · The paper itself

Abstract

Per- and polyfluoroalkyl substances (PFAS) are persistent environmental contaminants with poorly understood sublethal effects on insects. Perfluorooctanoic acid (PFOA), one of the most widely distributed legacy PFAS is increasingly recognized for altering organismal physiology beyond traditional toxicity endpoints. Here, we use the fruit fly

Indexed as

DevelopmentDrosophilaMetabolismPer- and Polyfluoroalkyl SubstancesPerfluorooctanoic acidPFASPFOA

Identifiers

PMID42367950
PMCPMC13307966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.