Evidence map›Paper›PMID 42367841›Full record

ArticlebioRxiv : the preprint server for biology2026

Dynamic geometry remapping of neural activity within frontal and subcortical areas during decision-making.

Frederic M Stoll, Neelima Valluru, Peter H Rudebeck

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Frederic M StollNash Family Department of Neuroscience, Lipschultz Center for Cognitive Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.ORCID 0000-0002-8642-8133
Neelima ValluruNash Family Department of Neuroscience, Lipschultz Center for Cognitive Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Peter H RudebeckNash Family Department of Neuroscience, Lipschultz Center for Cognitive Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.ORCID 0000-0002-1411-7555

Funding

Neural circuit mechanisms of affective probabilistic learningR01MH132064 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Peter Rudebeck · 2023 to 2026
$3.2M
A new approach to the role of prefrontal-limbic circuits in anxiety disordersR01MH110822 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI RUDEBECK, PETER · 2016 to 2020
$2.2M
NIMH NIH HHS R01 MH110822NIMH NIH HHS R01 MH132064
6 · The paper itself

Abstract

Decision-making involves dynamic evaluation of competing options. Recording 16,495 neurons across nine frontal and subcortical areas in macaques revealed brain-wide fluctuations between encoding the attributes of available options. These dynamic representations track deliberation and scale with decision difficulty. Instead of binding attribute information of different options together, our analyses show that these representations are associated with dynamic area- and attribute-specific changes in neural geometry.

Indexed as

amygdaladecision-makingelectrophysiologyfrontal cortexmonkeysneural geometryneuronsprobabilityrewardstriatum

Identifiers

PMID42367841
PMCPMC13308009

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.